Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | CBS | P35520 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10260846 | 0.87 | ACHE (0.44) | ACHELTA4HPTGS2CYP3A4HPGD | |
| SCHEMBL1050358 | 0.83 | CA1 (0.33) | ACHECA1CA2 | |
| SCHEMBL18458343 | 0.82 | ALDH1A1 (0.55) | ACHEBACE1LTA4HPTGS2CYP3A4 | |
| SCHEMBL25132436 | 0.82 | ACHE (0.44) | ACHEBACE1LTA4HPTGS2CYP3A4 | |
| SCHEMBL20644672 | 0.82 | ACHE (0.39) | ACHEPTGS2ALDH1A1 | |
| SCHEMBL351788 | 0.78 | ACHE (0.88) | ACHEBACE1LTA4HPTGS2CYP3A4 | |
| SCHEMBL30539351 | 0.78 | ACHE (0.50) | ACHEENPP2CA1CA2 | |
| SCHEMBL14761098 | 0.77 | ACHE (0.39) | ACHELTA4HPTGS2CYP3A4HPGD | |
| SCHEMBL17164362 | 0.73 | TSHR (0.55) | PTGS2CYP3A4HPGDHSD17B10ALOX15 | |
| SCHEMBL19002944 | 0.73 | TSHR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117209534-A | Phosphine ligand compound with phenol group and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-12-12 | — | — | CN | claimed |
| CN-117209534-A | Phosphine ligand compound with phenol group and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117209364-A | Substituted phenol compound and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| US-20220145012-A1 | ASSOCIATIVE POLYMERS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2022-05-12 | — | — | US | disclosed |
| US-20200040141-A1 | ASSOCIATIVE POLYMERS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-02-06 | — | — | US | disclosed |
| US-10472470-B2 | Associative polymers and related compositions, methods and systems | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-11-12 | — | — | US | disclosed |
| US-20190100642-A1 | ASSOCIATIVE POLYMERS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | UNITED STATES OF AMERICA AS REPRENSETED BY THE ADMINISTRATOR OF NASA | 2019-04-04 | — | — | US | disclosed |
| US-20190016859-A1 | ASSOCIATIVE POLYMERS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA | 2019-01-17 | — | — | US | disclosed |
| US-6451830-B1 | Use of substituted N,N-disubstituted non-fused heterocyclo amino compounds for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. | 2002-09-17 | — | — | US | disclosed |
| US-5238773-A | Alkaline developable photoresist composition containing radiation sensitive organosilicon compound with quinone diazide terminal groups | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0365881-A2 | Composition capable of being imaged and use of such a composition | International Business Machines Corporation (US) | 1990-05-02 | — | — | EP | disclosed |