Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 9/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22010140 | 0.91 | PDE9A (0.42) | PDE9ATSHRNPC1PKMRAB9A | |
| SCHEMBL25272291 | 0.91 | CYP1A2 (0.41) | PDE9ATSHRNPC1PKMRAB9A | |
| SCHEMBL25272167 | 0.88 | BTK (0.46) | PDE9ATSHRNPC1PKMRAB9A | |
| SCHEMBL25230775 | 0.87 | ALDH1A1 (0.42) | PDE9ATSHRNPC1PKMRAB9A | |
| SCHEMBL21903828 | 0.86 | KMT2A (0.42) | PDE9ATSHRKMT2AMEN1LMNA | |
| SCHEMBL21903640 | 0.86 | KMT2A (0.42) | PDE9ATSHRKMT2AMEN1LMNA | |
| SCHEMBL21903644 | 0.86 | KMT2A (0.42) | PDE9ATSHRKMT2AMEN1LMNA | |
| SCHEMBL30367690 | 0.86 | KMT2A (0.41) | PDE9ATSHRNPC1PKMRAB9A | |
| SCHEMBL24651143 | 0.85 | CYP1A2 (0.46) | PDE9ATSHRNPC1PKMRAB9A | |
| SCHEMBL24651144 | 0.84 | NPC1 (0.43) | PDE9ATSHRNPC1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019013562-A1 | NOVEL 1H-PYRAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 주식회사 대웅제약 | 2019-01-17 | — | — | WO | disclosed |