Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 15/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 15/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 15/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 13/20 | 0.40 |
| ▸ | TSHR | P16473 | 13/20 | 0.40 |
| ▸ | USP2 | O75604 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.40 |
| ▸ | PDE9A | O76083 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20645215 | 0.91 | PDE9A (0.48) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL22010140 | 0.90 | PDE9A (0.42) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL25230775 | 0.89 | ALDH1A1 (0.42) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL25272167 | 0.86 | BTK (0.46) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL30367690 | 0.84 | KMT2A (0.41) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL24651143 | 0.83 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL24651144 | 0.83 | NPC1 (0.43) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL21903524 | 0.82 | EPHX2 (0.44) | ALDH1A1PDE9AKMT2AMEN1LMNA | |
| SCHEMBL21903828 | 0.81 | KMT2A (0.42) | TSHRALDH1A1PDE9AMAPK1KMT2A | |
| SCHEMBL21903640 | 0.81 | KMT2A (0.42) | TSHRALDH1A1PDE9AMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192691-A1 | HETEROCYCLIC COMPOUNDS AS BTK INHIBITORS | BEIJING INNOCARE PHARMA TECH CO LTD (CN) | 2023-06-22 | — | — | US | disclosed |
| US-20230192691-A1 | HETEROCYCLIC COMPOUNDS AS BTK INHIBITORS | BEIJING INNOCARE PHARMA TECH CO LTD (CN) | 2023-06-22 | — | — | US | disclosed |
| US-20230192691-A1 | HETEROCYCLIC COMPOUNDS AS BTK INHIBITORS | BEIJING INNOCARE PHARMA TECH CO LTD (CN) | 2023-06-22 | — | — | US | disclosed |
| CN-114075190-A | Heterocyclic BTK inhibitors | 北京诺诚健华医药科技有限公司 | 2022-02-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192691-A1 | HETEROCYCLIC COMPOUNDS AS BTK INHIBITORS | BTK, SYK, LYN | CYP1A2 2657/4885CYP3A4 2261/4885CYP2C19 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.