Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29297718 | 0.84 | RIPK1 (0.55) | RIPK1 | |
| SCHEMBL23353355 | 0.82 | RIPK1 (0.53) | RIPK1 | |
| SCHEMBL20645944 | 0.73 | RIPK1 (0.64) | RIPK1 | |
| SCHEMBL23219840 | 0.71 | RIPK1 (0.50) | RIPK1 | |
| SCHEMBL24743557 | 0.70 | RIPK1 (0.36) | RIPK1 | |
| SCHEMBL24990756 | 0.70 | RIPK1 (0.69) | RIPK1 | |
| SCHEMBL20641141 | 0.69 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL20640677 | 0.69 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL20640756 | 0.69 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL20904022 | 0.67 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019012063-A1 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2019-01-17 | — | — | WO | disclosed |