Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | HPGDS | O60760 | 2/20 | 0.48 |
| ▸ | QRFPR | Q96P65 | 3/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24823292 | 0.89 | ALDH1A1 (0.54) | CTSBOPRD1OPRM1OPRK1PSMB5 | |
| SCHEMBL9978223 | 0.89 | PSMB5 (0.56) | FCER2MMP1HPGDSPSMB5CA12 | |
| SCHEMBL24183726 | 0.89 | PSMB5 (0.56) | FCER2MMP1HPGDSPSMB5CA12 | |
| SCHEMBL29337392 | 0.87 | ACE (0.54) | PSMB5 | |
| SCHEMBL24183714 | 0.87 | FAAH (0.53) | CTSBQRFPROPRD1OPRM1PSMB5 | |
| SCHEMBL22749410 | 0.86 | OPRD1 (0.52) | FCER2MMP1CTSBHPGDSOPRD1 | |
| SCHEMBL22749409 | 0.86 | OPRD1 (0.52) | FCER2MMP1CTSBHPGDSOPRD1 | |
| SCHEMBL15003956 | 0.86 | QRFPR (0.56) | FCER2MMP1HPGDSQRFPR | |
| SCHEMBL17177755 | 0.86 | QRFPR (0.56) | FCER2MMP1HPGDSQRFPR | |
| SCHEMBL18515624 | 0.86 | OPRD1 (0.53) | CTSBOPRD1OPRM1OPRK1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466976-A1 | ANTI-HER2 ANTIBODY-DRUG CONJUGATE | Daiichi Sankyo Company, Limited (JP) | 2019-04-10 | — | — | EP | disclosed |
| EP-3101032-B1 | ANTI-HER2 ANTIBODY-DRUG CONJUGATE | DAIICHI SANKYO CO LTD (JP) | 2019-01-16 | — | — | EP | disclosed |