SCHEMBL2064904

SCHEMBL2064904

FC(F)(F)C(Cl)CC(Cl)(Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16564439 0.81
SCHEMBL8084183 0.81 ALDH1A1 (0.35) ALDH1A1HSD17B10
SCHEMBL30542872 0.79 ALDH1A1 (0.33) ALDH1A1HSD17B10
SCHEMBL2389415 0.78 ALDH1A1 (0.37) ALDH1A1HSD17B10
SCHEMBL23675050 0.77 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL2377911 0.73
SCHEMBL820288 0.67
SCHEMBL21591937 0.67
SCHEMBL653146 0.67
SCHEMBL3716863 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658632-A1 CO-PRODUCTION OF 1,1,1-TRIFLUOROPROPENE (1243ZF) AND E-1,1,1,4,4,4-HEXAFLUORO-2-BUTENE (E-1336MZZ) The Chemours Company FC, LLC (US) 2025-12-10 EP claimed
WO-2024222187-A1 HIGH SPECIFIC SURFACE AREA CHROMIUM-BASED CATALYST WITH BORON-BASED PORES AND METHOD FOR PREPARING HIGH RATIO OF Z-FLUORINE-CONTAINING OLEFIN/E-FLUORINE-CONTAINING OLEFIN 泉州宇极新材料科技有限公司 2024-10-31 WO claimed
WO-2024163379-A1 CO-PRODUCTION OF 1,1,1-TRIFLUOROPROPENE (1243ZF) AND E-1,1,1,4,4,4-HEXAFLUORO-2-BUTENE (E-1336MZZ) THE CHEMOURS COMPANY FC, LLC (US) 2024-08-08 WO claimed
US-20230074227-A1 PROCESS TO PRODUCE (Z)-1,1,1,4,4,4-HEXAFLUORO-2-BUTENE AND INTERMEDIATES THE CHEMOURS COMPANY FC, LLC (US) 2023-03-09 US claimed
CN-112194561-B Preparation method of cis-hexafluoro-2-butene 西安近代化学研究所 2022-11-11 CN claimed
US-11390574-B2 Process for producing 1,1,3-trichloro-4,4,4-trifluorobut-1-ene THE CHEMOURS COMPANY FC, LLC (US) 2022-07-19 US claimed
CN-109721465-B Method for preparing trans-1, 1,1,4,4, 4-hexafluoro-2-butene 西安近代化学研究所 2022-03-15 CN claimed
CN-109553506-B Method for synthesizing trans-1, 1,1,4,4, 4-hexafluoro-2-butene 西安近代化学研究所 2021-10-01 CN claimed
US-20210188743-A1 Process and Intermediates for Preparing (E)-1,1,1,4,4,4-hexafluorobut-2-ene THE CHEMOURS COMPANY FC, LLC (US) 2021-06-24 US claimed
CN-112194561-A Preparation method of cis-hexafluoro-2-butene 西安近代化学研究所 2021-01-08 CN claimed
EP-3720834-A1 PROCESS AND INTERMEDIATES FOR PREPARING 1,1,3-TRICHLORO-4,4,4-TRIFLUOROBUT-1-ENE AND (E)-1,1,1,4,4,4-HEXAFLUOROBUT-2-ENE The Chemours Company FC, LLC (US) 2020-10-14 EP claimed
CN-111433177-A Processes and intermediates for the preparation of 1,1, 3-trichloro-4, 4, 4-trifluorobut-1-ene and (E) -1,1,1,4,4, 4-hexafluorobut-2-ene 科慕埃弗西有限公司 2020-07-17 CN claimed
WO-2019113052-A1 PROCESS AND INTERMEDIATES FOR PREPARING 1,1,3-TRICHLORO-4,4,4-TRIFLUOROBUT-1-ENE AND (E)-1,1,1,4,4,4-HEXAFLUOROBUT-2-ENE THE CHEMOURS COMPANY FC, LLC (US) 2019-06-13 WO claimed
CN-109721465-A It is a kind of to prepare anti-form-1, the method for 1,1,4,4,4- hexafluoro -2- butylene 西安近代化学研究所 2019-05-07 CN claimed
CN-109678650-A A kind of preparation method of the chloro- 4,4,4- trifluorobutane of 1,1,1,3- tetra- 西安近代化学研究所 2019-04-26 CN claimed
CN-109553506-A A kind of method of synthesis of trans -1,1,1,4,4,4- hexafluoro -2- butylene 西安近代化学研究所 2019-04-02 CN claimed
CN-106687430-A Processes for the production of z 1,1,1,4,4,4 hexafluoro 2-butene 科慕埃弗西有限公司 2017-05-17 CN claimed
WO-2015142981-A1 PROCESSES FOR THE PRODUCTION OF Z 1,1,1,4,4,4 HEXAFLUORO 2-BUTENE E I DU PONT DE NEMOURS AND COMPANY (US) 2015-09-24 WO claimed
EP-4658632-A1 CO-PRODUCTION OF 1,1,1-TRIFLUOROPROPENE (1243ZF) AND E-1,1,1,4,4,4-HEXAFLUORO-2-BUTENE (E-1336MZZ) The Chemours Company FC, LLC (US) 2025-12-10 EP disclosed
WO-2007059468-A1 FIRE EXTINGUISHING AND FIRE SUPPRESSION COMPOSITIONS COMPRISING UNSATURATE FLOUOROCARBONS GREAT LAKES CHEMICAL CORPORATION (US) 2007-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210188743-A1 Process and Intermediates for Preparing (E)-1,1,1,4,4,4-hexafluorobut-2-ene FRG1, PFN1, TOE1 ALDH1A1 2452/4885HSD17B10 3350/4885
US-11390574-B2 Process for producing 1,1,3-trichloro-4,4,4-trifluorobut-1-ene PFN1, TOE1, FRG1 ALDH1A1 1927/4885HSD17B10 2883/4885
US-20230074227-A1 PROCESS TO PRODUCE (Z)-1,1,1,4,4,4-HEXAFLUORO-2-BUTENE AND INTERMEDIATES ZYX, TMEM14C, ZRANB2 ALDH1A1 1926/4885HSD17B10 2271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.