Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CIT | O14578 | 2/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20649070 | 0.84 | EPHX2 (0.35) | TNIKHDAC1SLC2A1P2RX3LTA4H | |
| SCHEMBL14130 | 0.79 | MC4R (0.37) | HDAC1OPRM1OPRK1OPRL1 | |
| SCHEMBL20648912 | 0.79 | HDAC1 (0.34) | TNIKHDAC1SLC2A1HDAC6 | |
| SCHEMBL20649005 | 0.74 | SPHK1 (0.37) | SPHK1JAK2JAK3RAB9ACIT | |
| SCHEMBL20648866 | 0.71 | SPHK1 (0.36) | SPHK1HDAC1JAK2JAK3RAB9A | |
| SCHEMBL14137 | 0.70 | MC4R (0.42) | — | |
| SCHEMBL20648941 | 0.70 | CIT (0.50) | SPHK1RAB9ACIT | |
| SCHEMBL20648931 | 0.67 | CA2 (0.34) | SPHK1JAK2JAK3RAB9ACIT | |
| SCHEMBL20649206 | 0.67 | MAPT (0.45) | SPHK1RAB9ACIT | |
| SCHEMBL20649208 | 0.66 | SPHK1 (0.34) | SPHK1RAB9ACIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019013789-A1 | ANTIMICROBIAL COMPOUNDS | CURZA GLOBAL, LLC (US) | 2019-01-17 | — | — | WO | disclosed |