Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20648979 | 1.00 | SPHK1 (0.34) | SPHK1SMN1; SMN2RAB9AMAPTCA2 | |
| SCHEMBL20648931 | 0.89 | CA2 (0.34) | SPHK1SMN1; SMN2RAB9ACA2AAK1 | |
| SCHEMBL20648886 | 0.84 | TP53 (0.34) | SMN1; SMN2MAPTCA2KDM4EALDH1A1 | |
| SCHEMBL20648880 | 0.84 | TP53 (0.34) | SMN1; SMN2MAPTCA2KDM4EALDH1A1 | |
| SCHEMBL20649206 | 0.83 | MAPT (0.45) | SPHK1SMN1; SMN2RAB9AMAPTAAK1 | |
| SCHEMBL20648878 | 0.83 | TP53 (0.34) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL20649005 | 0.78 | SPHK1 (0.37) | SPHK1SMN1; SMN2RAB9AMAPTAAK1 | |
| SCHEMBL20648866 | 0.77 | SPHK1 (0.36) | SPHK1SMN1; SMN2RAB9AMAPTAAK1 | |
| SCHEMBL20649249 | 0.76 | HRH2 (0.40) | SPHK1HTR1FHTR1DHTR1BMEN1 | |
| SCHEMBL20648883 | 0.73 | MAP3K5 (0.36) | SMN1; SMN2RAB9AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019013789-A1 | ANTIMICROBIAL COMPOUNDS | CURZA GLOBAL, LLC (US) | 2019-01-17 | — | — | WO | disclosed |