Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | MTOR | P42345 | 3/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.34 |
| ▸ | HTR1F | P30939 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | CIT | O14578 | 2/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20648894 | 0.84 | MAPT (0.43) | MAPTRAB9APIK3CAMTORPIK3CG | |
| SCHEMBL20648915 | 0.84 | MAPT (0.43) | MAPTRAB9APIK3CAMTORPIK3CG | |
| SCHEMBL20648979 | 0.83 | SPHK1 (0.34) | MAPTSPHK1SMN1; SMN2RAB9AHTR1F | |
| SCHEMBL20649208 | 0.83 | SPHK1 (0.34) | MAPTSPHK1SMN1; SMN2RAB9AHTR1F | |
| SCHEMBL20649005 | 0.80 | SPHK1 (0.37) | MAPTSPHK1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL20648866 | 0.79 | SPHK1 (0.36) | MAPTSPHK1SMN1; SMN2RAB9AADORA2A | |
| SCHEMBL20648931 | 0.75 | CA2 (0.34) | SPHK1SMN1; SMN2RAB9AADORA2ANPC1 | |
| SCHEMBL20649249 | 0.73 | HRH2 (0.40) | SPHK1PIK3CAMTORHTR1FMCHR1 | |
| SCHEMBL20649100 | 0.71 | SPHK1 (0.32) | MAPTSPHK1CIT | |
| SCHEMBL20648941 | 0.70 | CIT (0.50) | SPHK1SMN1; SMN2RAB9AADORA2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019013789-A1 | ANTIMICROBIAL COMPOUNDS | CURZA GLOBAL, LLC (US) | 2019-01-17 | — | — | WO | disclosed |