Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20640320 | 0.81 | LMNA (0.39) | NPC1RAB9AMAPTSMN1; SMN2OPRM1 | |
| SCHEMBL20648951 | 0.75 | SCN1A (0.36) | NPC1RAB9AOPRM1OPRL1MEN1 | |
| SCHEMBL20640300 | 0.70 | LMNA (0.37) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL21875682 | 0.70 | ALDH1A1 (0.41) | F2F10NPC1RAB9AGAA | |
| SCHEMBL21875681 | 0.70 | ALDH1A1 (0.41) | F2F10NPC1RAB9AGAA | |
| SCHEMBL20640338 | 0.70 | LMNA (0.36) | NPC1RAB9AMAPTSMN1; SMN2HRH3 | |
| SCHEMBL30183293 | 0.68 | F2 (0.33) | F2F10 | |
| SCHEMBL20649026 | 0.68 | F2 (0.52) | F2F10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30183306 | 0.68 | F2 (0.32) | F2F10 | |
| SCHEMBL20640322 | 0.66 | LMNA (0.41) | NPC1RAB9AMAPTSMN1; SMN2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011715-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES AS CHOLINE KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2019-01-17 | — | — | WO | disclosed |