Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.36 |
| ▸ | HTR1F | P30939 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20648913 | 1.00 | QPCT (0.37) | QPCTMAP3K5ABL1RIN1HTR1F | |
| SCHEMBL20648904 | 0.92 | MAP3K5 (0.37) | QPCTMAP3K5ABL1RIN1HTR1F | |
| SCHEMBL20649017 | 0.90 | TRPV4 (0.38) | QPCTMAP3K5ABL1RIN1HTR1F | |
| SCHEMBL20648905 | 0.90 | TRPV4 (0.38) | QPCTMAP3K5ABL1RIN1HTR1F | |
| SCHEMBL20649249 | 0.85 | HRH2 (0.40) | QPCTMAP3K5ABL1RIN1HTR1F | |
| SCHEMBL20648911 | 0.84 | MAP3K5 (0.39) | QPCTMAP3K5ABL1RIN1HTR1F | |
| SCHEMBL20648776 | 0.83 | MAP3K5 (0.39) | MAP3K5ABL1RIN1POLBMEN1 | |
| SCHEMBL20649188 | 0.82 | MAP3K5 (0.37) | MAP3K5ABL1RIN1HTR1FPOLB | |
| SCHEMBL20648898 | 0.82 | MAP3K5 (0.37) | MAP3K5ABL1RIN1HTR1FPOLB | |
| SCHEMBL20649215 | 0.80 | MAP3K5 (0.46) | MAP3K5ABL1RIN1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019013789-A1 | ANTIMICROBIAL COMPOUNDS | CURZA GLOBAL, LLC (US) | 2019-01-17 | — | — | WO | disclosed |