Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.36 |
| ▸ | HTR1F | P30939 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20648913 | 0.85 | QPCT (0.37) | QPCTABL1RIN1HTR1FMCHR1 | |
| SCHEMBL20649248 | 0.85 | QPCT (0.37) | QPCTABL1RIN1HTR1FMCHR1 | |
| SCHEMBL20648866 | 0.77 | SPHK1 (0.36) | ABL1RIN1SPHK1KMT2A | |
| SCHEMBL20648911 | 0.77 | MAP3K5 (0.39) | HRH2HRH1QPCTABL1RIN1 | |
| SCHEMBL20648645 | 0.76 | ABL1 (0.36) | HRH2HRH1ABL1RIN1SPHK1 | |
| SCHEMBL20648904 | 0.76 | MAP3K5 (0.37) | QPCTABL1RIN1HTR1FDRD2 | |
| SCHEMBL20648931 | 0.76 | CA2 (0.34) | ABL1RIN1SPHK1 | |
| SCHEMBL20649005 | 0.76 | SPHK1 (0.37) | ABL1RIN1SPHK1 | |
| SCHEMBL20649208 | 0.76 | SPHK1 (0.34) | ABL1RIN1HTR1FSPHK1MCHR1 | |
| SCHEMBL20648979 | 0.76 | SPHK1 (0.34) | ABL1RIN1HTR1FSPHK1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019013789-A1 | ANTIMICROBIAL COMPOUNDS | CURZA GLOBAL, LLC (US) | 2019-01-17 | — | — | WO | disclosed |