SCHEMBL2064945

SCHEMBL2064945

COC(=O)CCC(=O)P(=O)(O)OC.[NaH]

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.54
LMNA P02545 3/20 0.41
KDM4E B2RXH2 1/20 0.41
KMT2A Q03164 3/20 0.39
ALDH1A1 P00352 3/20 0.39
HSD17B10 Q99714 2/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
MEN1 O00255 2/20 0.38
CA12 O43570 1/20 0.36
CA14 Q9ULX7 1/20 0.36
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
CYP1A2 P05177 1/20 0.33
ATM Q13315 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11130894 0.83 TSHR (0.59) TSHRLMNAKDM4EKMT2AALDH1A1
SCHEMBL30617931 0.80 TSHR (0.62) TSHRLMNAKDM4EKMT2AALDH1A1
SCHEMBL28638146 0.79 TSHR (0.54) TSHRLMNAKDM4EKMT2AALDH1A1
SCHEMBL29467562 0.78 TSHR (0.59) TSHRLMNAKDM4EKMT2AALDH1A1
SCHEMBL11134833 0.78 TSHR (0.59) TSHRLMNAKDM4EKMT2AALDH1A1
SCHEMBL11130896 0.77 TSHR (0.56) TSHRLMNAKDM4EKMT2AALDH1A1
SCHEMBL11136461 0.77 TSHR (0.56) TSHRLMNAKDM4EKMT2AALDH1A1
SCHEMBL11131570 0.77 TSHR (0.56) TSHRLMNAKDM4EKMT2AALDH1A1
Dimethyl Succinate SCHEMBL7778900 0.76 TSHR (0.93) TSHRLMNAKDM4EKMT2AALDH1A1
Dimethyl Succinate SCHEMBL28040641 0.76 TSHR (0.93) TSHRLMNAKDM4EKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240164993-A1 ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME KURARAY NORITAKE DENTAL INC. (JP) 2024-05-23 US disclosed
US-11607370-B2 Dental composition KURARAY NORITAKE DENTAL INC. (JP) 2023-03-21 US disclosed
EP-3782598-B1 ADHESIVE COMPOSITION FOR DENTAL USE KURARAY NORITAKE DENTAL INC (JP) 2023-02-15 EP disclosed
US-11547639-B2 Dental composition containing platinum nanoparticles KURARAY NORITAKE DENTAL INC. (JP) 2023-01-10 US disclosed
EP-3900694-A1 DENTAL ADHESIVE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2021-10-27 EP disclosed
US-20210186823-A1 DENTAL COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2021-06-24 US disclosed
EP-3782598-A1 ADHESIVE COMPOSITION FOR DENTAL USE Kuraray Noritake Dental Inc. (JP) 2021-02-24 EP disclosed
US-20200390661-A1 DENTAL COMPOSITION CONTAINING PLATINUM NANOPARTICLES KURARAY NORITAKE DENTAL INC. (JP) 2020-12-17 US disclosed
EP-3725288-A1 DENTAL COMPOSITION CONTAINING PLATINUM NANOPARTICLES Kuraray Noritake Dental Inc. (JP) 2020-10-21 EP disclosed
EP-3701930-A1 DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2020-09-02 EP disclosed
EP-2070935-B1 NOVEL COMPOUND, COMPOSITION COMPRISING THE SAME, AND PROCESS FOR PRODUCTION OF POLYMERIZABLE AMIDE KURARAY NORITAKE DENTAL INC (JP) 2015-01-07 EP disclosed
US-8552088-B2 Cement for dental applications KURARAY NORITAKE DENTAL INC. (JP) 2013-10-08 US disclosed
US-8148571-B2 Compound, composition comprising the same, and process for production of polymerizable amide KURARAY MEDICAL INC. (JP) 2012-04-03 US disclosed
US-20100267856-A1 CEMENT FOR DENTAL APPLICATIONS KURARAY MEDICAL INC. (JP) 2010-10-21 US disclosed
EP-2226060-A1 CEMENT FOR DENTAL APPLICATIONS Kuraray Medical Inc. (JP) 2010-09-08 EP disclosed
US-20100076157-A1 NOVEL COMPOUND, COMPOSITION COMPRISING THE SAME, AND PROCESS FOR PRODUCTION OF POLYMERIZABLE AMIDE KURARAY MEDICAL INC. (JP) 2010-03-25 US disclosed
EP-2070935-A1 NOVEL COMPOUND, COMPOSITION COMPRISING THE SAME, AND PROCESS FOR PRODUCTION OF POLYMERIZABLE AMIDE Kuraray Medical Inc. (JP) 2009-06-17 EP disclosed
EP-0009348-B1 PESTICIDALLY ACTIVE SALTS AND COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR MANUFACTURE AND USE FBC LIMITED (GB) 1983-07-20 EP disclosed
US-4339443-A Compounds and compositions FBC LIMITED (GB) 1982-07-13 US disclosed
EP-0009348-A2 Pesticidally active salts and compositions containing them and processes for their manufacture and use FBC LIMITED (GB) 1980-04-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11607370-B2 Dental composition ITGAL, ITGA1, ITGB3 TSHR 4827/4885LMNA 737/4885KDM4E 1144/4885
US-20210186823-A1 DENTAL COMPOSITION ITGAL, ITGA1, ITGB3 TSHR 4827/4885LMNA 737/4885KDM4E 1144/4885
US-20100076157-A1 NOVEL COMPOUND, COMPOSITION COMPRISING THE SAME, AND PROCESS FOR PRODUCTION OF POLYMERIZABLE AMIDE H1-0, H1-4, H1-2 TSHR 1712/4885LMNA 3598/4885KDM4E 2587/4885
US-20240164993-A1 ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME MSL1, ITGA1, ASH2L TSHR 4172/4885LMNA 3123/4885KDM4E 1685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.