SCHEMBL20649485

SCHEMBL20649485

O=C(CCN1CCN(CCC(=O)N(CCO)CCO)CC1)N(CCO)CCO

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
POLB P06746 2/20 0.38
L3MBTL1 Q9Y468 3/20 0.36
TP53 P04637 3/20 0.35
GLA P06280 1/20 0.34
KDM4E B2RXH2 1/20 0.33
PAOX Q6QHF9 1/20 0.32
TERT O14746 1/20 0.32
TSHR P16473 1/20 0.32
HSD11B1 P28845 1/20 0.32
DRD2 P14416 1/20 0.32
HTR2A P28223 1/20 0.32
HTR7 P34969 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29070245 0.87 GLA (0.53) ALDH1A1MAPTGLAKDM4E
SCHEMBL20649482 0.87 POLB (0.36) ALDH1A1MAPTPOLBL3MBTL1TP53
SCHEMBL21795200 0.84 ALDH1A1 (0.31) ALDH1A1
SCHEMBL20649480 0.82 OPRM1 (0.36) ALDH1A1DRD2HTR2AHTR7KCNH2
SCHEMBL25658569 0.81 CHRM2 (0.31) ALDH1A1
SCHEMBL1232870 0.77 ALDH1A1 (0.41) ALDH1A1MAPTPOLBKDM4E
SCHEMBL1387466 0.74 ALDH1A1 (0.39) ALDH1A1MAPTPOLBKDM4E
SCHEMBL132324 0.72 LMNA (0.46) ALDH1A1POLB
SCHEMBL29407499 0.72 LMNA (0.52) ALDH1A1POLB
SCHEMBL7134198 0.71 HSD17B10 (0.41) ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021112095-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR PRODUCING LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2021-06-10 WO disclosed
US-11028323-B2 Liquid crystal aligning agent containing crosslinking agent and polymer that has site having isocyanate group and/or blocked isocyanate group and site having photoreactivity, liquid crystal alignment film, and liquid crystal display element NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2021-06-08 US disclosed
US-10921650-B2 Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2021-02-16 US disclosed
WO-2020145175-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2020-07-16 WO disclosed
WO-2020138259-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, LIQUID CRYSTAL DISPLAY ELEMENT, AND NOVEL MONOMER 日産化学株式会社 2020-07-02 WO disclosed
WO-2020045548-A1 METHOD FOR PRODUCING LIQUID CRYSTAL ALIGNMENT FILM, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2020-03-05 WO disclosed
US-20190023987-A1 LIQUID CRYSTAL ALIGNING AGENT CONTAINING CROSSLINKING AGENT AND POLYMER THAT HAS SITE HAVING ISOCYANATE GROUP AND/OR BLOCKED ISOCYANATE GROUP AND SITE HAVING PHOTOREACTIVITY, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-01-24 US disclosed
US-20190018289-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-01-17 US disclosed