Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135665 | 0.97 | TSHR (0.50) | TSHRCYP3A4MEN1KMT2ATHRB | |
| SCHEMBL9356772 | 0.97 | TSHR (0.50) | TSHRCYP3A4MEN1KMT2ATHRB | |
| SCHEMBL64901 | 0.92 | HTT (0.50) | TSHRCYP3A4MEN1KMT2ATHRB | |
| SCHEMBL26838517 | 0.91 | TSHR (0.44) | TSHRCYP3A4MEN1KMT2ATHRB | |
| SCHEMBL20394653 | 0.90 | MEN1 (0.50) | TSHRCYP3A4MEN1KMT2ATHRB | |
| SCHEMBL12120261 | 0.90 | HTT (0.54) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL12120263 | 0.90 | HTT (0.54) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL9549348 | 0.90 | HTT (0.54) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL10422513 | 0.90 | HTT (0.54) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL12120266 | 0.90 | HTT (0.54) | TSHRMEN1KMT2ATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222159-B1 | INTERMEDIATES FOR MAKING A BENZOFURAN OR BENZOTHIOPHENE DERIVATIVE NITRATED IN POSITION 5 AND USES THEREOF | RHODIA CHIMIE SA (FR) | 2005-06-01 | — | — | EP | claimed |
| US-20050113596-A1 | Nitrating a 2-(2-formylphenoxy) or 2-(2-formylphenylsulfido) alkyl ester or alkoic acid in the presence of sulfuric acid | SHASUN PHARMA SOLUTIONS, INC. | 2005-05-26 | — | — | US | claimed |
| JP-2003512347-A | — | — | 2003-04-02 | — | — | JP | claimed |
| EP-1222159-A2 | INTERMEDIATES FOR MAKING A BENZOFURAN OR BENZOTHIOPHENE DERIVATIVE NITRATED IN POSITION 5 AND USES THEREOF | RHODIA CHIMIE (FR) | 2002-07-17 | — | — | EP | claimed |
| WO-2001028974-A2 | INTERMEDIATES FOR MAKING A BENZOFURAN OR BENZOTHIOPHENE DERIVATIVE NITRATED IN POSITION 5 AND USES THEREOF | RHODIA CHIMIE (FR) | 2001-04-26 | — | — | WO | claimed |
| US-4479022-A | ETHER, ALKALINE BASE CATALYST COMPLEXES | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-10-23 | — | — | US | claimed |
| US-4417048-A | N-alkylation of organonitrogen compounds | RHONE-POULENC SPECIALTIES CHIMIQUES (FR) | 1983-11-22 | — | — | US | claimed |
| US-4369145-A | Preparation of fluorobenzenesulfonyl fluorides by exchange fluorination | RHONE-POULENC INDUSTRIES (FR) | 1983-01-18 | — | — | US | claimed |
| US-4362855-A | Polymerization of polysiloxanes | RHONE-POULENC INDUSTRIES (FR) | 1982-12-07 | — | — | US | claimed |
| US-4346244-A | Preparation of chloroalkoxybenzenes | RHONE-POULENC INDUSTRIES (FR) | 1982-08-24 | — | — | US | claimed |
| US-4322369-A | Preparation of alkyl cyanoacetates | RHONE-POULENC INDUSTRIES (FR) | 1982-03-30 | — | — | US | claimed |
| US-8795942-B2 | Positive resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-08-05 | — | — | US | disclosed |
| US-8148053-B2 | DNA sequenceing, biochemical immobilization, and genetic diagnosis; forming monomolecular film using (alkoxyalkoxy)alkylsilane(triol and/or halide) such as 10-(methoxymethoxy)dodecyltrimethoxysilane which forms hydroxyl groups when exposed to acid; forming polysulfonates; radiation with high energy beams | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| US-8057981-B2 | Resist composition, resist protective coating composition, and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-11-15 | — | — | US | disclosed |
| US-8057981-B2 | Resist composition, resist protective coating composition, and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-11-15 | — | — | US | disclosed |
| US-4369145-A | Preparation of fluorobenzenesulfonyl fluorides by exchange fluorination | RHONE-POULENC INDUSTRIES (FR) | 1983-01-18 | — | — | US | disclosed |
| US-4362855-A | Polymerization of polysiloxanes | RHONE-POULENC INDUSTRIES (FR) | 1982-12-07 | — | — | US | disclosed |
| US-4346244-A | Preparation of chloroalkoxybenzenes | RHONE-POULENC INDUSTRIES (FR) | 1982-08-24 | — | — | US | disclosed |
| US-4322369-A | Preparation of alkyl cyanoacetates | RHONE-POULENC INDUSTRIES (FR) | 1982-03-30 | — | — | US | disclosed |
| US-4273915-A | TRIS/OXYALKYL/AMINE, APROTIC SOLVENT, EPOXY RESIN | RHONE-POULENC INDUSTRIES (FR) | 1981-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113596-A1 | Nitrating a 2-(2-formylphenoxy) or 2-(2-formylphenylsulfido) alkyl ester or alkoic acid in the presence of sulfuric acid | SULT1A1, SULT1E1, FPR1 | TSHR 2507/4885CYP3A4 125/4885MEN1 3851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.