SCHEMBL20650360

SCHEMBL20650360

Cc1ccccc1N(I)c1ccccc1C

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
ACHE P22303 2/20 0.47
SIGMAR1 Q99720 1/20 0.38
ALDH1A1 P00352 5/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
LMNA P02545 2/20 0.37
CYP3A4 P08684 3/20 0.36
TRPM8 Q7Z2W7 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21549184 0.85 ACHE (0.39) TSHRACHESIGMAR1ALDH1A1CA1
SCHEMBL24032237 0.83 CYP2A6 (0.54) TSHRSIGMAR1ALDH1A1CYP3A4TDP1
SCHEMBL7123510 0.81 ACHE (0.45) TSHRACHESIGMAR1ALDH1A1CA1
SCHEMBL516435 0.77 TSHR (0.53) TSHRACHESIGMAR1ALDH1A1CA1
SCHEMBL29521738 0.77 TSHR (0.53) TSHRACHESIGMAR1ALDH1A1CA1
SCHEMBL20650050 0.76 TSHR (0.39) TSHRACHEALDH1A1LMNATDP1
SCHEMBL8280381 0.76 ACHE (0.45) TSHRACHESIGMAR1ALDH1A1CA1
SCHEMBL22317583 0.75 LMNA (0.43) TSHRACHESIGMAR1ALDH1A1LMNA
SCHEMBL23633819 0.75 ACHE (0.39) TSHRACHESIGMAR1ALDH1A1CA1
Hydrochloric Acid SCHEMBL9135314 0.74 TSHR (0.50) TSHRACHESIGMAR1ALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed
EP-3428152-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2019-01-16 EP disclosed