SCHEMBL8280381

SCHEMBL8280381

Cc1ccccc1N(C)[SiH3]

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.45
TSHR P16473 1/20 0.45
SIGMAR1 Q99720 1/20 0.41
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
LMNA P02545 2/20 0.36
ALDH1A1 P00352 3/20 0.36
NOTUM Q6P988 1/20 0.36
CYP3A4 P08684 3/20 0.35
TRPM8 Q7Z2W7 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP1A2 P05177 2/20 0.33
C5AR1 P21730 1/20 0.33
CYP2A6 P11509 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16612270 0.81 TSHR (0.47) ACHETSHRSIGMAR1CA1CA2
SCHEMBL30800114 0.81 TSHR (0.47) ACHETSHRSIGMAR1CA1CA2
SCHEMBL6054716 0.80 TRPA1 (0.41) ACHETSHRSIGMAR1CA1CA2
SCHEMBL27755669 0.79 TSHR (0.45) ACHETSHRSIGMAR1CA1CA2
Hydrochloric Acid SCHEMBL27745837 0.78 TRPA1 (0.39) ACHETSHRCA1CA2CA7
SCHEMBL2620728 0.78 ACHE (0.50) ACHETSHRSIGMAR1CA1CA2
SCHEMBL29435133 0.78 TSHR (0.50) ACHETSHRSIGMAR1CA1CA2
SCHEMBL29239 0.78 TSHR (0.50) ACHETSHRSIGMAR1CA1CA2
Hydrochloric Acid SCHEMBL2869837 0.76 TSHR (0.47) ACHETSHRSIGMAR1CA1CA2
SCHEMBL20650360 0.76 TSHR (0.47) ACHETSHRSIGMAR1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114127197-A Curable resin composition, cured film formed therefrom, and electronic device having cured film 三星SDI株式会社 2022-03-01 CN disclosed
US-8912353-B2 Organoaminosilane precursors and methods for depositing films comprising same AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-12-16 US disclosed
US-8912353-B2 Organoaminosilane precursors and methods for depositing films comprising same AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-12-16 US disclosed
EP-2392691-B1 Organoaminosilane precursors and methods for depositing films comprising the same AIR PROD & CHEM (US) 2014-09-03 EP disclosed
US-20120128897-A1 Organoaminosilane Precursors and Methods for Depositing Films Comprising Same AIR PRODUCTS AND CHEMICALS, INC. (US) 2012-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120128897-A1 Organoaminosilane Precursors and Methods for Depositing Films Comprising Same C1S, C9, C5 ACHE 1849/4885TSHR 4015/4885SIGMAR1 1397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.