SCHEMBL20650417

SCHEMBL20650417

Cc1cccc2c1oc1c(N(I)c3ccccc3OC(F)(F)F)cccc12

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 2/20 0.32
ALDH1A1 P00352 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SCN9A Q15858 1/20 0.31
C1R P00736 1/20 0.31
EPHX2 P34913 1/20 0.31
RPS6KA2 Q15349 1/20 0.31
MCL1 Q07820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20172815 0.86 S1PR1 (0.33) S1PR1ALDH1A1L3MBTL1SCN9AC1R
SCHEMBL20650461 0.85 P2RY1 (0.31) ALDH1A1L3MBTL1C1REPHX2RPS6KA2
SCHEMBL20650497 0.85 HSD11B1 (0.34) S1PR1L3MBTL1SCN9AC1REPHX2
SCHEMBL20649744 0.85 EPHX2 (0.37) ALDH1A1L3MBTL1C1REPHX2RPS6KA2
SCHEMBL20650311 0.84 SLC6A3 (0.35) ALDH1A1L3MBTL1C1REPHX2
SCHEMBL20650717 0.84 KCNK3 (0.38) ALDH1A1L3MBTL1
SCHEMBL20650222 0.82 SLC22A12 (0.32) L3MBTL1
SCHEMBL20650801 0.81 SLC6A4 (0.34) EPHX2MCL1
SCHEMBL21020257 0.81 MCL1 (0.38) S1PR1ALDH1A1L3MBTL1SCN9AC1R
SCHEMBL20650423 0.81 ELANE (0.33) MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed
EP-3428152-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2019-01-16 EP disclosed