SCHEMBL20650461

SCHEMBL20650461

CC(C)(C)c1cccc2c1oc1c(N(I)c3ccccc3OC(F)(F)F)cccc12

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 3/20 0.31
P2RY14 Q15391 1/20 0.31
ALDH1A1 P00352 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
HSD11B1 P28845 1/20 0.30
C1R P00736 1/20 0.30
RPS6KA2 Q15349 1/20 0.30
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20650497 0.90 HSD11B1 (0.34) L3MBTL1HSD11B1C1REPHX2
SCHEMBL20172834 0.87 HTR6 (0.32) P2RY1P2RY14ALDH1A1L3MBTL1HSD11B1
SCHEMBL20650417 0.85 S1PR1 (0.32) ALDH1A1L3MBTL1C1RRPS6KA2EPHX2
SCHEMBL20650472 0.84 KIF11 (0.31)
SCHEMBL20650482 0.83 KIF11 (0.34) ALDH1A1
SCHEMBL20649744 0.83 EPHX2 (0.37) ALDH1A1L3MBTL1C1RRPS6KA2EPHX2
SCHEMBL20650311 0.82 SLC6A3 (0.35) ALDH1A1L3MBTL1C1REPHX2
SCHEMBL20650717 0.82 KCNK3 (0.38) P2RY1P2RY14ALDH1A1L3MBTL1
SCHEMBL20650257 0.82 P2RY1 (0.35) P2RY1P2RY14
SCHEMBL20650124 0.81 KIF11 (0.31) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed
EP-3428152-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2019-01-16 EP disclosed