Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21297523 | 0.86 | ASAH1 (0.43) | ALDH1A1 | |
| SCHEMBL25707541 | 0.83 | ASAH1 (0.40) | CYP2D6HTR2AALDH1A1 | |
| SCHEMBL889842 | 0.82 | MEN1 (0.38) | CYP2D6HTR2AKIF11MEN1KMT2A | |
| SCHEMBL18349844 | 0.82 | CYP2D6 (0.42) | CYP2D6HTR2AKIF11MEN1KMT2A | |
| SCHEMBL23373405 | 0.81 | ASAH1 (0.43) | ALDH1A1 | |
| SCHEMBL13575130 | 0.79 | PLA2G2A (0.44) | CYP2D6HTR2ASLC6A1 | |
| SCHEMBL21297524 | 0.79 | ASAH1 (0.41) | ALDH1A1 | |
| SCHEMBL890352 | 0.78 | ALDH1A1 (0.35) | KIF11MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL22380805 | 0.77 | SLC6A11 (0.44) | CYP2D6HTR2AKIF11MEN1KMT2A | |
| SCHEMBL20371106 | 0.77 | ALDH1A1 (0.38) | CYP2D6HTR2AKIF11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011829-A1 | IMPROVED PROCESS FOR PREPARING IMETELSTAT | JANSSEN PHARMACEUTICA NV (BE) | 2019-01-17 | — | — | WO | disclosed |