Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13400119 | 0.79 | ACHE (0.48) | GAAMAPTHRH3MC4RSIGMAR1 | |
| SCHEMBL14614976 | 0.79 | LMNA (0.45) | GAAMAPTHRH3TSHRSIGMAR1 | |
| SCHEMBL31599453 | 0.79 | GAA (0.44) | GAAMAPTHRH3TSHRSIGMAR1 | |
| SCHEMBL10082773 | 0.78 | LMNA (0.47) | GAAMAPTHRH3TSHRSIGMAR1 | |
| SCHEMBL14615180 | 0.76 | GAA (0.43) | GAAMAPTHRH3CREBBPTSHR | |
| SCHEMBL7686692 | 0.76 | DRD4 (0.53) | MC4RMEN1KMT2A | |
| SCHEMBL14615106 | 0.75 | GAA (0.62) | GAAMAPTMC4RALDH1A1MEN1 | |
| SCHEMBL20274110 | 0.72 | HRH3 (0.60) | HRH3TSHRSIGMAR1 | |
| SCHEMBL2450511 | 0.70 | CREBBP (0.59) | GAAMAPTCREBBPMTNR1A | |
| SCHEMBL1193549 | 0.70 | CREBBP (0.59) | GAAMAPTCREBBPMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-A1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | Merial Inc. (US) | 2019-01-16 | — | — | EP | disclosed |