Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Octadecanoic Acid Amide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetradecanamide SCHEMBL2065731 | 1.00 | TP53 (0.37) | TP53SLC25A20KDM4ECYP2D6TSHR | |
| Palmitamide SCHEMBL2065209 | 1.00 | TP53 (0.37) | TP53SLC25A20KDM4ECYP2D6TSHR | |
| Glycinebetaine SCHEMBL1065800 | 0.87 | GPR84 (0.41) | TP53CYP2D6TSHRMAPTNFKB1 | |
| Glycinebetaine SCHEMBL2132643 | 0.87 | GPR84 (0.41) | TP53CYP2D6TSHRMAPTNFKB1 | |
| Glycinebetaine SCHEMBL156318 | 0.87 | GPR84 (0.41) | TP53CYP2D6TSHRMAPTNFKB1 | |
| Glycinebetaine SCHEMBL2133338 | 0.87 | GPR84 (0.41) | TP53CYP2D6TSHRMAPTNFKB1 | |
| Glycinebetaine SCHEMBL3889766 | 0.87 | GPR84 (0.41) | TP53CYP2D6TSHRMAPTNFKB1 | |
| Glycinebetaine SCHEMBL2131138 | 0.87 | GPR84 (0.41) | TP53CYP2D6TSHRMAPTNFKB1 | |
| Glycinebetaine SCHEMBL2135218 | 0.87 | GPR84 (0.41) | TP53CYP2D6TSHRMAPTNFKB1 | |
| SCHEMBL9633678 | 0.87 | SOAT1 (0.47) | TP53KDM4ETSHRMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1895979-B1 | COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE | DOW CORNING TORAY CO LTD (JP) | 2014-03-12 | — | — | EP | disclosed |
| US-8147854-B2 | Cosmetics comprising a modified organopolysiloxane | DOW CORNING TORAY COMPANY, LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20100028391-A1 | Cosmetics Comprising A Modified Organopolysiloxane | DOW CORNING TORAY COMPANY, LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| EP-1895979-A1 | COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE | Dow Corning Toray Co., Ltd. (JP) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006137576-A1 | COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE | DOW CORNING TORAY CO., LTD. (JP) | 2006-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100028391-A1 | Cosmetics Comprising A Modified Organopolysiloxane | H1-0, H1-2, CHRM1 | TP53 2174/4885SLC25A20 4238/4885KDM4E 2493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.