Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL2132643 | 1.00 | GPR84 (0.41) | GPR84FFAR1MAPTLCKPPARD | |
| Glycinebetaine SCHEMBL3889766 | 1.00 | GPR84 (0.41) | GPR84FFAR1MAPTLCKPPARD | |
| Glycinebetaine SCHEMBL156318 | 1.00 | GPR84 (0.41) | GPR84FFAR1MAPTLCKPPARD | |
| Glycinebetaine SCHEMBL2135218 | 1.00 | GPR84 (0.41) | GPR84FFAR1MAPTLCKPPARD | |
| Glycinebetaine SCHEMBL2131138 | 1.00 | GPR84 (0.41) | GPR84FFAR1MAPTLCKPPARD | |
| Glycinebetaine SCHEMBL1065800 | 1.00 | GPR84 (0.41) | GPR84FFAR1MAPTLCKPPARD | |
| Glycinebetaine SCHEMBL2131980 | 0.92 | FABP3 (0.46) | FFAR1MAPTPPARDNPSR1 | |
| Betaine SCHEMBL22534547 | 0.88 | TSHR (0.44) | GPR84FFAR1MAPTLCKPPARD | |
| Glycinebetaine SCHEMBL6416801 | 0.88 | ACE2 (0.43) | GPR84FFAR1MAPTLCKPPARD | |
| Glycinebetaine SCHEMBL1893593 | 0.88 | CHRM1 (0.39) | GRIK1GRIK2NFKB1SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150315712-A1 | CLEANING COMPOSITION FOR METAL ARTICLES | PARKER-HANNIFIN CORPORATION | 2015-11-05 | — | — | US | disclosed |
| US-9114088-B2 | Cosmetic preparation for hair and method for application thereof | HOYU CO., LTD. (JP) | 2015-08-25 | — | — | US | disclosed |
| WO-2014092756-A1 | CLEANING COMPOSITION FOR METAL ARTICLES | PARKER-HANNIFIN CORPORATION (US) | 2014-06-19 | — | — | WO | disclosed |
| US-8288329-B2 | Hair-treatment composition and hair-treatment method using same | HOYU CO., LTD (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20120207689-A1 | COSMETIC PREPARATION FOR HAIR AND METHOD FOR APPLICATION THEREOF | HOYU CO., LTD. (JP) | 2012-08-16 | — | — | US | disclosed |
| US-20120100091-A1 | HAIR-TREATMENT COMPOSITION AND HAIR-TREATMENT METHOD USING SAME | HOYU CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
| US-7501390-B2 | Concentrated neutral detergent composition comprising an alkanesulfonic acid salt, a polyoxyalkylene alkyle ether, an alkyl polyglucoside, and water | JOHNSONDIVERSEY, INC. (US) | 2009-03-10 | — | — | US | disclosed |
| EP-1725639-B1 | CONCENTRATED NEUTRAL DETERGENT COMPOSITION | JOHNSON DIVERSEY INC (US) | 2009-01-07 | — | — | EP | disclosed |
| US-20070287649-A1 | Concentrated Neutral Detergent Composition | DIVERSEY, INC. (FORMERLY KNOWN AS JOHNSONDIVERSEY, INC.) | 2007-12-13 | — | — | US | disclosed |
| EP-1725639-A1 | CONCENTRATED NEUTRAL DETERGENT COMPOSITION | JohnsonDiversey, Inc. (US) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005093028-A1 | CONCENTRATED NEUTRAL DETERGENT COMPOSITION | JOHNSONDIVERSEY, INC. (US) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100091-A1 | HAIR-TREATMENT COMPOSITION AND HAIR-TREATMENT METHOD USING SAME | AADAT, BHMT2, BCAT2 | GPR84 202/4885FFAR1 49/4885MAPT 4022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.