Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL2133338 | 1.00 | GPR84 (0.41) | GPR84FFAR1MAPTLCKPPARD | |
| Glycinebetaine SCHEMBL2132643 | 1.00 | GPR84 (0.41) | GPR84FFAR1MAPTLCKPPARD | |
| Glycinebetaine SCHEMBL3889766 | 1.00 | GPR84 (0.41) | GPR84FFAR1MAPTLCKPPARD | |
| Glycinebetaine SCHEMBL156318 | 1.00 | GPR84 (0.41) | GPR84FFAR1MAPTLCKPPARD | |
| Glycinebetaine SCHEMBL2135218 | 1.00 | GPR84 (0.41) | GPR84FFAR1MAPTLCKPPARD | |
| Glycinebetaine SCHEMBL2131138 | 1.00 | GPR84 (0.41) | GPR84FFAR1MAPTLCKPPARD | |
| Glycinebetaine SCHEMBL2131980 | 0.92 | FABP3 (0.46) | FFAR1MAPTPPARDNPSR1 | |
| Betaine SCHEMBL22534547 | 0.88 | TSHR (0.44) | GPR84FFAR1MAPTLCKPPARD | |
| Glycinebetaine SCHEMBL6416801 | 0.88 | ACE2 (0.43) | GPR84FFAR1MAPTLCKPPARD | |
| Glycinebetaine SCHEMBL1893593 | 0.88 | CHRM1 (0.39) | GRIK1GRIK2NFKB1SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9119991-B2 | Golf ball resin composition and golf ball | DUNLOP SPORTS CO. LTD. (JP) | 2015-09-01 | — | — | US | claimed |
| US-6261352-B1 | BETAINE, SULFO ESTER | THE PILOT INK CO., LTD. (JP) | 2001-07-17 | — | — | US | claimed |
| CN-118302149-A | Method for treating keratin materials or fibres for head gear articles | 花王株式会社 | 2024-07-05 | — | — | CN | disclosed |
| US-12012658-B2 | Composition, kit, and method for treating substrate | FUJIFILM CORPORATION (JP) | 2024-06-18 | — | — | US | disclosed |
| US-20240192100-A1 | METHOD FOR TREATING BIOLOGICAL SAMPLE | FUJIREBIO INC. (JP) | 2024-06-13 | — | — | US | disclosed |
| CN-118099430-A | Cathode for secondary battery and cathode slurry | 广东省皓智科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-114424365-B | Cathode for secondary battery and cathode slurry | 广东省皓智科技有限公司 | 2024-04-23 | — | — | CN | disclosed |
| US-11905452-B2 | Treatment agent for treating fibers, fibers and production method therefor, and fiber sheet and production method therefor | RESONAC CORPORATION (JP) | 2024-02-20 | — | — | US | disclosed |
| EP-4317451-A1 | METHOD FOR TREATING BIOLOGICAL SAMPLE | Fujirebio Inc. (JP) | 2024-02-07 | — | — | EP | disclosed |
| WO-2024014555-A1 | LIQUID DETERGENT COMPOSITION FOR DISHES | ライオン株式会社 | 2024-01-18 | — | — | WO | disclosed |
| WO-2024009754-A1 | SURFACTANT COMPOSITION AND CLEANING AGENT | 三洋化成工業株式会社 | 2024-01-11 | — | — | WO | disclosed |
| US-5759528-A | AMINE OXIDE SURFACTANT AND CYCLOHEXANE, CYCLOHEXENE OR CYCLOHEXANONE DERIVATIVE | INSTITUTE FOR ADVANCED SKIN RESEARCH, INC. (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0745389-A1 | COMPOSITION FOR TOPICAL APPLICATION | INSTITUTE FOR ADVANCED SKIN RESEARCH INC. (JP) | 1996-12-04 | — | — | EP | disclosed |
| EP-0702079-A2 | Low-irritant detergent compositions | Kao Corporation (JP) | 1996-03-20 | — | — | EP | disclosed |
| EP-0695936-A2 | A method for classifying and counting leukocytes | TOA MEDICAL ELECTRONICS CO., Ltd. (JP) | 1996-02-07 | — | — | EP | disclosed |
| EP-0660113-A2 | A reagent for analyzing leucocytes | TOA MEDICAL ELECTRONICS CO., LTD. (JP) | 1995-06-28 | — | — | EP | disclosed |
| EP-0356784-B1 | Liquid detergent composition | MITSUBISHI PETROCHEMICAL CO (JP) | 1993-11-10 | — | — | EP | disclosed |
| US-5116608-A | Quaternary ammonium ethyl mercaptan | SEIWA KASEI CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| US-5000877-A | Aqueous liquid detergent containing an N-acylaspartate and a betaine or imidazoline surfactant | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-03-19 | — | — | US | disclosed |
| EP-0361391-A2 | Permanent waving composition | SEIWA KASEI CO., LTD. (JP) | 1990-04-04 | — | — | EP | disclosed |