SCHEMBL2065266

SCHEMBL2065266

[O]S(=O)(=O)c1ccc(OS(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.43
CA1 P00915 6/20 0.43
APEX1 P27695 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
CA12 O43570 3/20 0.37
CA9 Q16790 3/20 0.37
CA7 P43166 1/20 0.37
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ENPP1 P22413 4/20 0.35
ENPP3 O14638 4/20 0.35
SOS1 Q07889 1/20 0.34
ENPP2 Q13822 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13924685 0.84 CA1 (0.42) CA2CA1CA12CA9CA7
SCHEMBL6304613 0.84 CA1 (0.42) CA2CA1APEX1TDP1CA12
SCHEMBL7600291 0.82 CA2 (0.46) CA2CA1TDP1CA12CA9
SCHEMBL2067020 0.79 CA12 (0.51) CA2CA1APEX1TDP1CA12
SCHEMBL3790743 0.79 CA1 (0.49) CA2CA1TDP1CA12CA9
SCHEMBL25703285 0.78 TDP1 (0.46) CA2CA1TDP1CA12CA7
SCHEMBL28640874 0.77 CA1 (0.57) CA2CA1CA12CA9CA7
SCHEMBL926640 0.76 CA1 (0.45) CA2CA1CA12CA9CA7
SCHEMBL4968694 0.76 CA2 (0.40) CA2CA1TDP1CA12CA9
SCHEMBL942031 0.75 CA2 (0.41) CA2CA1TDP1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148053-B2 DNA sequenceing, biochemical immobilization, and genetic diagnosis; forming monomolecular film using (alkoxyalkoxy)alkylsilane(triol and/or halide) such as 10-(methoxymethoxy)dodecyltrimethoxysilane which forms hydroxyl groups when exposed to acid; forming polysulfonates; radiation with high energy beams SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-04-03 US disclosed
US-7494760-B2 Photoacid generators, chemically amplified resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-02-24 US disclosed
US-20080233309-A1 Method for manufacturing substrate for making microarray SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-09-25 US disclosed
US-20070287096-A1 Photoacid generators, chemically amplified resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. 2007-12-13 US disclosed
US-6916591-B2 Photoacid generators, chemically amplified resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-07-12 US disclosed
US-20030215738-A1 Photoacid generators, chemically amplified resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030215738-A1 Photoacid generators, chemically amplified resist compositions, and patterning process CCNH, PAH, POLH CA2 1041/4885CA1 2097/4885APEX1 1455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.