Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 5/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 5/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3790743 | 0.83 | CA1 (0.49) | CA2CA1CA12CA9TDP1 | |
| SCHEMBL2065266 | 0.82 | CA2 (0.43) | CA2CA1SOS1CA12CA9 | |
| SCHEMBL13924685 | 0.81 | CA1 (0.42) | CA2CA1CA12CA9ENPP2 | |
| SCHEMBL6304613 | 0.81 | CA1 (0.42) | CA2CA1CA12CA9ENPP1 | |
| SCHEMBL926640 | 0.80 | CA1 (0.45) | CA2CA1CA12CA9MAPT | |
| SCHEMBL4968694 | 0.80 | CA2 (0.40) | CA2CA1CA12CA9MAPT | |
| SCHEMBL942031 | 0.80 | CA2 (0.41) | CA2CA1CA12CA9MAPT | |
| SCHEMBL4967638 | 0.77 | CA1 (0.47) | CA2CA1CA12CA9ENPP1 | |
| SCHEMBL4423397 | 0.77 | TDP1 (0.40) | CA2CA1CA12CA9ENPP1 | |
| SCHEMBL2437174 | 0.77 | TDP1 (0.40) | CA2CA1CA12CA9ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728760-B1 | Preparation of pentafluorophenyl compounds | ALBEMARLE CORP (US) | 2002-11-27 | — | — | EP | disclosed |