Dyrene

Dyrene

SCHEMBL2065280

C(=Cc1ccccc1)c1ccccc1.Clc1nc(Cl)nc(Nc2ccccc2Cl)n1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.77
▸ NFKB1 P19838 1/20 0.51
▸ MAPT P10636 5/20 0.47
▸ KMT2A Q03164 4/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ KDM4E B2RXH2 2/20 0.46
▸ ALDH1A1 P00352 2/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ EGFR P00533 1/20 0.45
▸ MMP1 P03956 1/20 0.45
▸ MMP2 P08253 1/20 0.45
▸ MMP9 P14780 1/20 0.45
▸ IGF1R P08069 1/20 0.43
▸ RAD52 P43351 1/20 0.43
▸ HDAC3 O15379 1/20 0.42
▸ HDAC1 Q13547 1/20 0.42
▸ HDAC2 Q92769 1/20 0.42
▸ HDAC6 Q9UBN7 1/20 0.42
▸ GRM4 Q14833 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dyrene SCHEMBL29364667 0.88 TSHR (1.00) TSHRNFKB1MAPTKMT2AMEN1
Dyrene SCHEMBL13280 0.88 TSHR (1.00) TSHRNFKB1MAPTKMT2AMEN1
Dyrene SCHEMBL6750152 0.88 TSHR (1.00) TSHRNFKB1MAPTKMT2AMEN1
Dyrene SCHEMBL1903290 0.88 TSHR (1.00) TSHRNFKB1MAPTKMT2AMEN1
Dyrene SCHEMBL8166670 0.88 TSHR (1.00) TSHRNFKB1MAPTKMT2AMEN1
Dyrene SCHEMBL133054 0.88 TSHR (1.00) TSHRNFKB1MAPTKMT2AMEN1
Dyrene SCHEMBL7045805 0.88 TSHR (0.73) TSHRNFKB1MAPTKMT2AMEN1
Dyrene SCHEMBL3326806 0.86 TSHR (0.96) TSHRNFKB1MAPTKMT2AMEN1
Dyrene SCHEMBL5745643 0.86 TSHR (0.96) TSHRNFKB1MAPTKMT2AMEN1
Dyrene SCHEMBL1284023 0.86 TSHR (0.96) TSHRNFKB1MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117511311-A Paint suitable for canvas printed by multiple inks and preparation process thereof 潍坊佳诚数码材料有限公司 2024-02-06 — — CN claimed
CN-112724094-A Novel environment-friendly disulfonic acid liquid fluorescent whitening agent and preparation method thereof 山西晋光化工有限公司 2021-04-30 — — CN claimed
CN-112695546-A Dyeing and finishing process for preventing staining of cotton knitted fabric 湖北际华针织有限公司 2021-04-23 — — CN claimed
CN-108795196-B Yellowing-resistant weak-solvent spray painting coating and preparation method thereof 广东艺都科技有限公司 2020-06-19 — — CN claimed
CN-111088124-A Special stilbene bistriazine fluorescent whitening agent for detergent and preparation method thereof 山西晋光化工有限公司 2020-05-01 — — CN claimed
US-10353334-B2 Printing methods HP INDIGO B.V. (NL) 2019-07-16 — — US claimed
US-10197935-B2 Liquid electrophotographic composition HP INDIGO B.V. (NL) 2019-02-05 — — US claimed
US-20180267419-A1 LIQUID ELECTROPHOTOGRAPHIC COMPOSITION HP INDIGO B.V. (NL) 2018-09-20 — — US claimed
EP-3097454-B1 LIQUID ELECTROPHOTOGRAPHIC COMPOSITION HP INDIGO BV (NL) 2018-09-05 — — EP claimed
US-10042274-B2 Primer composition and method HP INDIGO B.V. (NL) 2018-08-07 — — US claimed
CN-104460245-B A kind of colour paper development concentrate 保定乐凯照相化学有限公司 2018-07-20 — — CN claimed
US-9857715-B2 Liquid electrophotographic composition HEWLETT-PACKARD INDIGO B.V. (NL) 2018-01-02 — — US claimed
US-20170329244-A1 PRIMER COMPOSITION AND METHOD HP INDIGO B.V. (NL) 2017-11-16 — — US claimed
US-20170329268-A1 PRINTING METHODS HP INDIGO B.V. (NL) 2017-11-16 — — US claimed
EP-3097454-A1 LIQUID ELECTROPHOTOGRAPHIC COMPOSITION Hewlett-Packard Indigo B.V. (NL) 2016-11-30 — — EP claimed
US-20160342103-A1 LIQUID ELECTROPHOTOGRAPHIC COMPOSITION HEWLETT-PACKARD INDIGO B.V. (NL) 2016-11-24 — — US claimed
CN-104460245-A Color photographic paper developing concentrated solution BAODING LUCKY PHOTOGRAPH CHEMICAL CO LTD 2015-03-25 — — CN claimed
CN-1278717-A Hair care compositions comprising optical brighteners and hair conditioning agents PROCTER & GAMBLE (US) 2001-01-03 — — CN claimed
JP-58138687-A — — None — — JP disclosed
US-4123376-A AROMATIC SULFONAMIDE COLGATE-PALMOLIVE COMPANY (US) 1978-10-31 — — US disclosed
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