SCHEMBL20654752

SCHEMBL20654752

c1ccc(-c2ccc(-n3c4ccccc4c4cc(-n5c6cc(-c7ccc8c(c7)c7ccccc7n8-c7ccccc7)ccc6c6c(-c7ccc8cc(-n9c%10ccccc%10c%10cc(-n%11c%12ccccc%12c%12cc(-c%13ccc%14c(c%13)c%13ccccc%13n%14-c%13ccccc%13)ccc%12%11)ccc%109)c9ccccc9c8c7)cccc65)ccc43)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HDAC4 P56524 1/20 0.32
TSPO P30536 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20655091 0.92 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL11998195 0.89 L3MBTL1 (0.35) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL24525981 0.89 L3MBTL1 (0.37) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL24526011 0.89 L3MBTL1 (0.37) KDM4EATML3MBTL1HDAC4
SCHEMBL20655021 0.89 L3MBTL1 (0.42) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL24684586 0.88 KDM4E (0.36) KDM4EATML3MBTL1HDAC4
SCHEMBL20006904 0.88 L3MBTL1 (0.43) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL20654998 0.88 L3MBTL1 (0.43) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL21310207 0.88 L3MBTL1 (0.45) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL25671987 0.87 PDE6D (0.35) KDM4EATML3MBTL1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2020-07-07 US disclosed
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, L1CAM, AGO2 KDM4E 3248/4885ATM 2324/4885L3MBTL1 1678/4885
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element LEF1, L1CAM, AGO2 KDM4E 3248/4885ATM 2324/4885L3MBTL1 1678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.