⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12049857 | 0.83 | L3MBTL1 (0.31) | — | |
| SCHEMBL12769537 | 0.83 | L3MBTL1 (0.31) | — | |
| SCHEMBL10072846 | 0.80 | — | — | |
| SCHEMBL20654927 | 0.79 | — | — | |
| SCHEMBL21563220 | 0.79 | LGALS8 (0.31) | — | |
| SCHEMBL19146269 | 0.79 | — | — | |
| SCHEMBL12990383 | 0.79 | LGALS8 (0.31) | — | |
| SCHEMBL14643902 | 0.77 | — | — | |
| SCHEMBL13818671 | 0.77 | L3MBTL1 (0.33) | — | |
| SCHEMBL12583008 | 0.77 | L3MBTL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10604542-B2 | Cyclic dinucleotides for treating conditions associated with sting activity such as cancer | INNATE TUMOR IMMUNITY, INC. (US) | 2020-03-31 | — | — | US | disclosed |
| US-20190016750-A1 | CYCLIC DINUCLEOTIDES FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY SUCH AS CANCER | Innate Tumoir Immunity, Inc. (US) | 2019-01-17 | — | — | US | disclosed |