SCHEMBL2065535

SCHEMBL2065535

CCCc1ccc2nc(C(N)=O)cn2n1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.41
RAB9A P51151 4/20 0.41
NPC1 O15118 3/20 0.41
RXFP1 Q9HBX9 1/20 0.41
KMT2A Q03164 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.37
PDE10A Q9Y233 3/20 0.34
CA5A P35218 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PIK3CA P42336 1/20 0.32
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2067013 0.82 KDM4E (0.61) KDM4ERAB9ANPC1RXFP1KMT2A
SCHEMBL2066636 0.78 PDE10A (0.40) KDM4ERAB9ANPC1PDE10ASMN1; SMN2
SCHEMBL2066941 0.77 PDE10A (0.38) KDM4EPDE10APDCD1CD274
SCHEMBL30845857 0.77 RBP4 (0.46) KDM4ERAB9ANPC1RXFP1KMT2A
SCHEMBL2068243 0.75 PDE10A (0.53) KDM4EPDE10ASMN1; SMN2PDCD1CD274
SCHEMBL2067442 0.75 PDE10A (0.39) KDM4ERAB9ANPC1PDE10ASMN1; SMN2
SCHEMBL3343233 0.75 PIK3CA (0.44) PIK3CAPDCD1CD274
SCHEMBL23554705 0.74 KDM4E (0.40) KDM4ERAB9ANPC1RXFP1KMT2A
SCHEMBL2066059 0.74 PDE10A (0.54) RAB9ANPC1PDE10APDCD1CD274
SCHEMBL2066211 0.74 PDE10A (0.38) KDM4ERAB9ANPC1PDE10ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399381-B2 Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-03-19 US disclosed
US-8148524-B2 Process for producing sulfonyl chloride compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-03 US disclosed
EP-1932846-B1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2010-10-27 EP disclosed
US-7816526-B2 Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-10-19 US disclosed
US-20100160163-A1 Fused heterocyclic sulfonylurea compound, herbicide containing the same, and method for controlling weed with the same TANAKA YASUSHI 2010-06-24 US disclosed
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
EP-1932846-A1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SALL4, CLCN2, CLIC1 KDM4E 3606/4885RAB9A 1898/4885NPC1 2888/4885
US-20100160163-A1 Fused heterocyclic sulfonylurea compound, herbicide containing the same, and method for controlling weed with the same NOTUM, WEE1, DDT KDM4E 503/4885RAB9A 1275/4885NPC1 4711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.