Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20655563 | 0.95 | PTGER4 (0.37) | CHEK1HRH4PIK3CDPIK3CAKMT2A | |
| SCHEMBL20114587 | 0.94 | CHEK1 (0.40) | CHEK1HRH4PIK3CDPIK3CAKMT2A | |
| SCHEMBL20648358 | 0.93 | CYP11B2 (0.34) | CHEK1HRH4KMT2ACYP11B2GRM2 | |
| SCHEMBL20150412 | 0.93 | CASP3 (0.35) | CHEK1HRH4KMT2ACYP11B2GRM2 | |
| SCHEMBL20648310 | 0.92 | CHEK1 (0.32) | CHEK1HRH4PGR | |
| SCHEMBL20655221 | 0.91 | PIK3CD (0.36) | CHEK1HRH4PIK3CDPIK3CACYP11B2 | |
| SCHEMBL20655387 | 0.90 | CYP1A2 (0.40) | HRH4KMT2APGRMAPTMEN1 | |
| SCHEMBL20150391 | 0.90 | CHEK1 (0.36) | CHEK1HRH4PIK3CDPIK3CAKMT2A | |
| SCHEMBL20156218 | 0.89 | PTGER4 (0.39) | CHEK1HRH4PIK3CDPIK3CAKMT2A | |
| SCHEMBL20114574 | 0.89 | GABRA1 (0.39) | CHEK1KMT2APTGER4MEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11005048-B2 | Organic molecules, in particular for use in optoelectronic devices | CYNORA GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| US-20190019960-A1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190019960-A1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | OR10J3, OR51E2, ORC3 | CHEK1 3910/4885HRH4 2829/4885PIK3CD 4564/4885 |
| US-11005048-B2 | Organic molecules, in particular for use in optoelectronic devices | OR10J3, OR51E2, ORC3 | CHEK1 3910/4885HRH4 2829/4885PIK3CD 4564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.