Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 14/20 | 0.41 |
| ▸ | USP1 | O94782 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20656236 | 0.95 | P2RX3 (0.40) | P2RX3USP1ADORA3SMN1; SMN2 | |
| SCHEMBL20656030 | 0.94 | ADORA3 (0.41) | USP1ADORA3 | |
| SCHEMBL20656031 | 0.94 | PKM (0.41) | P2RX3USP1ADORA3MAPK1SMN1; SMN2 | |
| SCHEMBL24095606 | 0.93 | MDM2 (0.43) | P2RX3USP1ADORA3 | |
| SCHEMBL20652803 | 0.92 | P2RX3 (0.41) | P2RX3USP1ADORA3 | |
| SCHEMBL20656057 | 0.90 | ALOX5AP (0.36) | P2RX3USP1 | |
| SCHEMBL20656215 | 0.90 | P2RX3 (0.36) | P2RX3ADORA3MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL24095551 | 0.87 | P2RX3 (0.39) | P2RX3USP1ADORA3 | |
| SCHEMBL20655883 | 0.87 | P2RX3 (0.41) | P2RX3USP1SMN1; SMN2 | |
| SCHEMBL20652831 | 0.87 | P2RX3 (0.41) | P2RX3USP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011802-A1 | NOVEL SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-01-17 | — | — | WO | disclosed |