Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20656228 | 0.76 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL20656191 | 0.68 | CNOT7 (0.38) | MEN1KMT2ATGFBR1TGFBR2P2RX3 | |
| SCHEMBL11920854 | 0.62 | KMT2A (0.46) | MEN1KMT2ATGFBR1TGFBR2P2RX3 | |
| SCHEMBL22105453 | 0.61 | MEN1 (0.35) | MEN1KMT2ATGFBR1TGFBR2P2RX3 | |
| SCHEMBL29832042 | 0.60 | TGFBR1 (0.56) | MEN1KMT2ATGFBR1TGFBR2 | |
| SCHEMBL13529459 | 0.59 | MEN1 (0.41) | MEN1KMT2ATGFBR1TGFBR2P2RX3 | |
| SCHEMBL26018062 | 0.57 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL24553986 | 0.57 | MEN1 (0.47) | MEN1KMT2ATGFBR1TGFBR2P2RX3 | |
| SCHEMBL9576472 | 0.57 | MEN1 (0.43) | MEN1KMT2A | |
| SCHEMBL23703927 | 0.57 | KDM4C (0.51) | MEN1KMT2ATGFBR1TGFBR2P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011802-A1 | NOVEL SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-01-17 | — | — | WO | disclosed |