Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50205 | 0.78 | NOS2 (0.41) | NOS3NOS2DRD2DRD1DRD4 | |
| SCHEMBL2419709 | 0.73 | CES1 (0.36) | NOS3NOS2DRD2DRD1DRD4 | |
| SCHEMBL16256694 | 0.71 | CES1 (0.34) | NOS3NOS2DRD2DRD1DRD4 | |
| SCHEMBL12279756 | 0.71 | CES1 (0.34) | NOS3NOS2DRD2DRD1DRD4 | |
| SCHEMBL20655988 | 0.70 | NOS3 (0.33) | NOS3NOS2 | |
| SCHEMBL20260233 | 0.66 | CYP2A6 (0.33) | — | |
| SCHEMBL3290813 | 0.65 | MAOA (0.46) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL5949876 | 0.64 | NOS3 (0.33) | NOS3NOS2 | |
| SCHEMBL16256695 | 0.64 | CES1 (0.33) | NOS3NOS2DRD2DRD1DRD4 | |
| SCHEMBL1820514 | 0.64 | CES1 (0.41) | NOS3NOS2DRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011826-A1 | RING CLOSURE REACTION | MERCK PATENT GMBH (DE) | 2019-01-17 | — | — | WO | disclosed |