Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 9/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20656222 | 0.87 | P2RX3 (0.34) | P2RX3L3MBTL1 | |
| SCHEMBL18834301 | 0.71 | P2RX3 (0.40) | P2RX3 | |
| SCHEMBL20432229 | 0.71 | P2RX3 (0.49) | P2RX3 | |
| SCHEMBL20656002 | 0.71 | P2RX3 (0.45) | P2RX3L3MBTL1 | |
| SCHEMBL20656029 | 0.71 | P2RX3 (0.35) | P2RX3 | |
| SCHEMBL18833745 | 0.71 | P2RX3 (0.38) | P2RX3 | |
| SCHEMBL16028092 | 0.70 | P2RX3 (0.49) | P2RX3 | |
| SCHEMBL18834679 | 0.70 | TNF (0.50) | P2RX3 | |
| SCHEMBL20656191 | 0.70 | CNOT7 (0.38) | P2RX3 | |
| SCHEMBL16028142 | 0.70 | ALDH1A1 (0.44) | P2RX3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011802-A1 | NOVEL SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-01-17 | — | — | WO | disclosed |