Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | POLB | P06746 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20657355 | 0.78 | ALDH1A1 (0.62) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL4282643 | 0.78 | POLB (0.81) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL4282964 | 0.77 | KDM4E (0.81) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL4286750 | 0.77 | POLB (0.79) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL17318590 | 0.75 | MEN1 (0.80) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL17318501 | 0.74 | KDM4E (0.76) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL17318502 | 0.74 | KDM4E (1.00) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL17318499 | 0.74 | MAPT (1.00) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL17318629 | 0.73 | POLB (0.76) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL2526391 | 0.72 | NPC1 (1.00) | ALDH1A1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278971-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2023-09-07 | — | — | US | disclosed |
| US-20230278971-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2023-09-07 | — | — | US | disclosed |
| US-20230278971-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2023-09-07 | — | — | US | disclosed |
| US-20210309622-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2021-10-07 | — | — | US | disclosed |
| US-20210309622-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2021-10-07 | — | — | US | disclosed |
| US-11052078-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | VERSITECH LIMITED (CN) | 2021-07-06 | — | — | US | disclosed |
| US-11052078-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | VERSITECH LIMITED (CN) | 2021-07-06 | — | — | US | disclosed |
| US-11040949-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | VERSITECH LIMITED (CN) | 2021-06-22 | — | — | US | disclosed |
| US-11040949-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | VERSITECH LIMITED (CN) | 2021-06-22 | — | — | US | disclosed |
| US-20200392095-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | THE UNIVERSITY OF HONG KONG (HK) | 2020-12-17 | — | — | US | disclosed |
| US-20200392095-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | THE UNIVERSITY OF HONG KONG (HK) | 2020-12-17 | — | — | US | disclosed |
| US-20200261438-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | THE UNIVERSITY OF HONG KONG (HK) | 2020-08-20 | — | — | US | disclosed |
| US-20200261438-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | THE UNIVERSITY OF HONG KONG (HK) | 2020-08-20 | — | — | US | disclosed |
| US-20190022038-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2019-01-24 | — | — | US | disclosed |
| US-20190022038-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2019-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11040949-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | TYR, ALAD, NQO1 | ALDH1A1 295/4885POLB 212/4885KDM4E 4078/4885 |
| US-20200392095-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | ALDH1A1 295/4885POLB 212/4885KDM4E 4078/4885 |
| US-11052078-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | TYR, ALAD, NQO1 | ALDH1A1 295/4885POLB 212/4885KDM4E 4078/4885 |
| US-20210309622-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | ALDH1A1 295/4885POLB 212/4885KDM4E 4078/4885 |
| US-20200261438-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | ALDH1A1 295/4885POLB 212/4885KDM4E 4078/4885 |
| US-20230278971-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | ALDH1A1 295/4885POLB 212/4885KDM4E 4078/4885 |
| US-20190022038-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | ALDH1A1 295/4885POLB 212/4885KDM4E 4078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.