Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | ACR | P10323 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SCD | O00767 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20657285 | 0.78 | ALDH1A1 (0.64) | ALDH1A1POLBTDP1LMNASMN1; SMN2 | |
| SCHEMBL1140233 | 0.76 | CYP1A2 (0.60) | ALDH1A1POLBTDP1LMNASMN1; SMN2 | |
| SCHEMBL1140302 | 0.76 | MAPT (0.56) | ALDH1A1POLBTDP1LMNAKDM4E | |
| SCHEMBL1140119 | 0.76 | MEN1 (0.60) | ALDH1A1POLBTDP1LMNAKDM4E | |
| SCHEMBL1140378 | 0.76 | TDP1 (0.54) | ALDH1A1POLBTDP1LMNAKDM4E | |
| SCHEMBL8692256 | 0.76 | ALDH1A1 (0.68) | ALDH1A1POLBTDP1LMNASMN1; SMN2 | |
| SCHEMBL1140817 | 0.75 | KMT2A (0.59) | ALDH1A1POLBTDP1LMNASMN1; SMN2 | |
| SCHEMBL1140583 | 0.74 | MEN1 (0.55) | ALDH1A1POLBTDP1LMNASMN1; SMN2 | |
| SCHEMBL1140486 | 0.74 | TDP1 (0.54) | ALDH1A1POLBTDP1LMNAKDM4E | |
| SCHEMBL1140535 | 0.74 | ALDH1A1 (0.54) | ALDH1A1POLBTDP1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278971-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2023-09-07 | — | — | US | disclosed |
| US-20230278971-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2023-09-07 | — | — | US | disclosed |
| US-20210309622-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2021-10-07 | — | — | US | disclosed |
| US-20210309622-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2021-10-07 | — | — | US | disclosed |
| US-11052078-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | VERSITECH LIMITED (CN) | 2021-07-06 | — | — | US | disclosed |
| US-11052078-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | VERSITECH LIMITED (CN) | 2021-07-06 | — | — | US | disclosed |
| US-11040949-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | VERSITECH LIMITED (CN) | 2021-06-22 | — | — | US | disclosed |
| US-11040949-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | VERSITECH LIMITED (CN) | 2021-06-22 | — | — | US | disclosed |
| US-20200392095-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | THE UNIVERSITY OF HONG KONG (HK) | 2020-12-17 | — | — | US | disclosed |
| US-20200392095-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | THE UNIVERSITY OF HONG KONG (HK) | 2020-12-17 | — | — | US | disclosed |
| US-20200261438-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | THE UNIVERSITY OF HONG KONG (HK) | 2020-08-20 | — | — | US | disclosed |
| US-20200261438-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | THE UNIVERSITY OF HONG KONG (HK) | 2020-08-20 | — | — | US | disclosed |
| US-20190022038-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2019-01-24 | — | — | US | disclosed |
| US-20190022038-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2019-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11040949-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | TYR, ALAD, NQO1 | ALDH1A1 295/4885POLB 212/4885RXFP1 4131/4885 |
| US-20200392095-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | ALDH1A1 295/4885POLB 212/4885RXFP1 4131/4885 |
| US-11052078-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | TYR, ALAD, NQO1 | ALDH1A1 295/4885POLB 212/4885RXFP1 4131/4885 |
| US-20210309622-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | ALDH1A1 295/4885POLB 212/4885RXFP1 4131/4885 |
| US-20200261438-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | ALDH1A1 295/4885POLB 212/4885RXFP1 4131/4885 |
| US-20230278971-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | ALDH1A1 295/4885POLB 212/4885RXFP1 4131/4885 |
| US-20190022038-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | ALDH1A1 295/4885POLB 212/4885RXFP1 4131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.