Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.60 |
| ▸ | HTR3B | O95264 | 1/20 | 0.60 |
| ▸ | HTR3A | P46098 | 1/20 | 0.60 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.60 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | NOS3 | P29474 | 2/20 | 0.50 |
| ▸ | NOS1 | P29475 | 2/20 | 0.50 |
| ▸ | NOS2 | P35228 | 2/20 | 0.50 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19148200 | 1.00 | HTR3E (0.60) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20657404 | 0.85 | MPI (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20657403 | 0.85 | MPI (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5546949 | 0.82 | HTR3E (0.58) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5546945 | 0.82 | HTR3E (0.58) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL19149163 | 0.79 | NOS3 (0.60) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20657405 | 0.79 | NOS3 (0.60) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL19148574 | 0.77 | CRHR1 (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20657423 | 0.77 | CRHR1 (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20657441 | 0.77 | HTR3E (0.60) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266494-B2 | Process for the preparation of polyfluoroalkylated quinolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-04-23 | — | — | US | disclosed |
| US-20190023659-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023659-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | KCNQ1, KCNQ2, KCNQ4 | HTR3E 1006/4885HTR3B 571/4885HTR3A 965/4885 |
| US-10266494-B2 | Process for the preparation of polyfluoroalkylated quinolines | KCNQ1, KCNQ2, KCNQ4 | HTR3E 1006/4885HTR3B 571/4885HTR3A 965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.