SCHEMBL20658017

SCHEMBL20658017

CCO[SiH](Cc1ccccc1)OCC(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.35
HTT P42858 2/20 0.35
TP53 P04637 1/20 0.32
RCE1 Q9Y256 1/20 0.31
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31
LTA4H P09960 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL123780 0.84 TP53 (0.44) TP53TSHRLTA4H
SCHEMBL25329243 0.82 TP53 (0.42) TP53TSHRLTA4H
SCHEMBL3815801 0.79 TP53 (0.39) TP53MAPTTSHRLTA4H
SCHEMBL20658013 0.76 TP53 (0.34) KMT2AHTTTP53RCE1NPC1
SCHEMBL19809422 0.76 TP53 (0.37) KMT2ATP53NPC1MAPTTSHR
SCHEMBL4361108 0.73 TP53 (0.34) TP53TSHR
SCHEMBL19927062 0.73 LTA4H (0.37) KMT2ATP53NPC1TSHRLTA4H
SCHEMBL703150 0.70 TP53 (0.41) KMT2ATP53NPC1MAPTTSHR
SCHEMBL3482077 0.69 TP53 (0.44) TP53MAPTTSHRLTA4H
SCHEMBL49102 0.68 TP53 (0.42) TP53MAPTTSHRLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108473684-B Process for producing siloxane polymer 东丽精细化工株式会社 2023-05-12 CN disclosed
US-10647821-B2 Production process for silicone polymer TORAY FINE CHEMICALS CO., LTD. (JP) 2020-05-12 US disclosed
US-20190023848-A1 PRODUCTION PROCESS FOR SILICONE POLYMER TORAY FINE CHEMICALS CO., LTD. (JP) 2019-01-24 US disclosed