SCHEMBL49102

SCHEMBL49102

CO[SiH](Cc1ccccc1)OC

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.42
LTA4H P09960 1/20 0.41
TSHR P16473 4/20 0.40
CALM1 P0DP23 1/20 0.39
ALDH1A1 P00352 4/20 0.37
IDO1 P14902 2/20 0.37
LOXL2 Q9Y4K0 1/20 0.36
TRPA1 O75762 1/20 0.36
CA4 P22748 1/20 0.36
KDM4E B2RXH2 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
AGXT P21549 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9505652 0.98 TP53 (0.40) TP53LTA4HTSHRCALM1ALDH1A1
SCHEMBL8830313 0.93 LTA4H (0.38) TP53LTA4HTSHRCALM1ALDH1A1
Dimethylamine SCHEMBL7748343 0.93 LTA4H (0.42) TP53LTA4HTSHRCALM1IDO1
SCHEMBL19809259 0.85 LTA4H (0.39) TP53LTA4HTSHRALDH1A1CA4
SCHEMBL3815801 0.85 TP53 (0.39) TP53LTA4HTSHRCALM1ALDH1A1
SCHEMBL15455621 0.84 LTA4H (0.32) TP53LTA4HTSHR
SCHEMBL19809244 0.82 TP53 (0.37) TP53LTA4HTSHRALDH1A1TDP1
SCHEMBL20658040 0.82 LTA4H (0.33) TP53LTA4HTSHRCALM1ALDH1A1
SCHEMBL29215801 0.80 TP53 (0.32) TP53LTA4H
SCHEMBL8440990 0.80 TSHR (0.32) TP53LTA4HTSHRALDH1A1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4454 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617947-B2 Flame-retardant flexible coating composition, flame-retardant product having flame-retardant flexible coating layer and method for manufacturing the same AXEED INC. (KR) 2026-05-05 US claimed
US-20260118766-A1 Silicon containing coating compositions and uses thereof PIBOND OY (FI) 2026-04-30 US claimed
EP-4015592-B1 CURABLE CONDENSATION COMPOUNDS ON THE BASIS OF ALKOXY-FUNCTIONAL POLYSILOXANES EVONIK OPERATIONS GMBH (DE) 2026-03-18 EP claimed
EP-4673493-A1 SILICON CONTAINING COATING COMPOSITIONS AND USES THEREOF Pibond Oy (FI) 2026-01-07 EP claimed
EP-4649356-A1 UNDERLAYER AND METHODS FOR EUV LITHOGRAPHY Brewer Science, Inc. (US) 2025-11-19 EP claimed
US-12460081-B2 Curable condensation compounds based on alkoxy-functional polysiloxanes EVONIK OPERATIONS GMBH (DE) 2025-11-04 US claimed
EP-4588956-A1 NEW SILANE MONOMERS FOR ORGANOSILOXANE POLYMERS Optitune Oy (FI) 2025-07-23 EP claimed
US-12331164-B2 Curable siloxane resin composition KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-06-17 US claimed
US-20250188332-A1 LIGNIN-BASED ADHESIVES UNIVERSITY OF SOUTH CAROLINA 2025-06-12 US claimed
WO-2025078379-A1 EASY TO CLEAN COATINGS WITH LOW FINGERPRINT VISIBILITY OPTITUNE OY (FI) 2025-04-17 WO claimed
US-4930879-A Synthetic resin lens NIPPON OIL AND FATS CO., LTD. (JP) 1990-06-05 US claimed
US-4911864-A Mixture of (meth)acryloyl group and electroconductive particles NIPPON OIL CO., LTD. (JP) 1990-03-27 US claimed
EP-0281365-A2 Curable compositions NIPPON OIL CO. LTD. (JP) 1988-09-07 EP claimed
US-4766011-A TREATING INTERSTICLES WITH AROMATIC RADICAL CONTAINING SILANE DOW CORNING CORPORATION (US) 1988-08-23 US claimed
EP-0274101-A2 Restoring stranded conductor electrical distribution cable DOW CORNING CORPORATION (US) 1988-07-13 EP claimed
US-4678768-A POLYMERS OF HIGH STEREOREGULARITY AND BULK DENSITY TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1987-07-07 US claimed
US-4611892-A Synthetic resin ophthalmic lens having a surface hard coat SEIKO EPSON CORPORATION (JP) 1986-09-16 US claimed
US-4525421-A POLYSILOXANES, POLYETHERS, POLYEDOXIDES, POLYETHERSILOXANES KABUSHIKI KAISHA SUWA SEIKOSHA (JP) 1985-06-25 US claimed
US-4141926-A Method for preparing epoxy-modified silicon resins SHIN-ETSU CHEMICAL CO., LTD. (JP) 1979-02-27 US claimed
US-4039666-A ANTICONVULSANT PHENYLSILANES DOW CORNING CORPORATION (US) 1977-08-02 US claimed