SCHEMBL2065950

SCHEMBL2065950

CCCc1ccc2nc(CC)c(S(N)(=O)=O)n2n1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.33
CA1 P00915 2/20 0.32
CA9 Q16790 2/20 0.32
AKT1 P31749 1/20 0.31
AKT2 P31751 1/20 0.31
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2066226 0.93 CA2 (0.34) CA2CA1CA9PDE10A
SCHEMBL2066641 0.86 PDE10A (0.30) PDE10A
SCHEMBL2066413 0.85 PDE10A (0.38) CA2CA1CA9PDE10A
SCHEMBL2065746 0.84 PDE10A (0.37) CA2CA1PDE10A
SCHEMBL2066797 0.84 CA2 (0.33) CA2PDE10A
SCHEMBL2066698 0.84 CA2 (0.33) CA2PDE10A
SCHEMBL2066634 0.83 CA2 (0.33) CA2
SCHEMBL3344359 0.82 KDM4E (0.35) CA2CA1CA9AKT1AKT2
SCHEMBL2068142 0.82 CA2 (0.32) CA2CA1CA9
SCHEMBL3342867 0.81 TNF (0.48) CA2AKT1AKT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148524-B2 Process for producing sulfonyl chloride compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-03 US disclosed
EP-1932846-B1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2010-10-27 EP disclosed
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
EP-1932846-A1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SALL4, CLCN2, CLIC1 CA2 176/4885CA1 1402/4885CA9 760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.