Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2066200 | 0.92 | CA2 (0.36) | PDE10ATNFCA2CA12CA1 | |
| SCHEMBL2065760 | 0.89 | TNF (0.35) | PDE10ATNFCA2CA12CA1 | |
| SCHEMBL2066696 | 0.88 | PDE10A (0.37) | PDE10ANPC1RAB9A | |
| SCHEMBL2066226 | 0.85 | CA2 (0.34) | PDE10ACA2CA1 | |
| SCHEMBL2066413 | 0.85 | PDE10A (0.38) | PDE10ACA2CA12CA1 | |
| SCHEMBL2065950 | 0.84 | CA2 (0.33) | PDE10ACA2CA1 | |
| SCHEMBL2066698 | 0.84 | CA2 (0.33) | PDE10ACA2 | |
| SCHEMBL2066797 | 0.84 | CA2 (0.33) | PDE10ACA2NPC1RAB9A | |
| SCHEMBL2066634 | 0.83 | CA2 (0.33) | CA2 | |
| SCHEMBL2066427 | 0.83 | TLR7 (0.34) | PDE10ATNFCA2CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279207-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2024-08-22 | — | — | US | disclosed |
| EP-4229048-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| US-8399381-B2 | Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |
| US-8399381-B2 | Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |
| US-8148524-B2 | Process for producing sulfonyl chloride compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-04-03 | — | — | US | disclosed |
| EP-1932846-B1 | METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2010-10-27 | — | — | EP | disclosed |
| US-7816526-B2 | Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-19 | — | — | US | disclosed |
| US-7816526-B2 | Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-19 | — | — | US | disclosed |
| US-20100160163-A1 | Fused heterocyclic sulfonylurea compound, herbicide containing the same, and method for controlling weed with the same | TANAKA YASUSHI | 2010-06-24 | — | — | US | disclosed |
| EP-1541575-B1 | NOVEL PROCESS FOR PRODUCING IMIDAZO(1,2-B)PYRIDAZINE DERIVATIVE | SUMITOMO CHEMICAL CO (JP) | 2010-03-03 | — | — | EP | disclosed |
| US-20090247748-A1 | PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-10-01 | — | — | US | disclosed |
| EP-1466527-B1 | FUSED HETEROCYCLIC SULFONYLUREA COMPOUND, HERBICIDE CONTAINING THE SAME, AND METHOD OF CONTROLLING WEED WITH THE SAME | SUMITOMO CHEMICAL CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| EP-1932846-A1 | METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-06-18 | — | — | EP | disclosed |
| US-7307165-B2 | Process for producting imidazo[1,2-b]pyridazine derivative | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2007-12-11 | — | — | US | disclosed |
| US-7307165-B2 | Process for producting imidazo[1,2-b]pyridazine derivative | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2007-12-11 | — | — | US | disclosed |
| US-20050171108-A1 | Novel process for producting imidazo[1,2-b]pyridazine derivative | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-08-04 | — | — | US | disclosed |
| EP-1541575-A1 | NOVEL PROCESS FOR PRODUCING IMIDAZO(1,2-B)PYRIDAZINE DERIVATIVE | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-20050032650-A1 | Fused heterocyclic sulfonylurea compound herbicide containing the same and method of controlling weed with the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-02-10 | — | — | US | disclosed |
| EP-1466527-A1 | FUSED HETEROCYCLIC SULFONYLUREA COMPOUND, HERBICIDE CONTAINING THE SAME, AND METHOD OF CONTROLLING WEED WITH THE SAME | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2004-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171108-A1 | Novel process for producting imidazo[1,2-b]pyridazine derivative | POR, CBR3, NR2C2 | PDE10A 4593/4885TNF 4860/4885CA2 1422/4885 |
| US-20090247748-A1 | PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND | SALL4, CLCN2, CLIC1 | PDE10A 3486/4885TNF 4785/4885CA2 176/4885 |
| US-20100160163-A1 | Fused heterocyclic sulfonylurea compound, herbicide containing the same, and method for controlling weed with the same | NOTUM, WEE1, DDT | PDE10A 741/4885TNF 3641/4885CA2 609/4885 |
| US-20240279207-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | KAT6A, KAT6B, KAT2A | PDE10A 4330/4885TNF 3414/4885CA2 2865/4885 |
| US-20050032650-A1 | Fused heterocyclic sulfonylurea compound herbicide containing the same and method of controlling weed with the same | NOTUM, WEE1, DDT | PDE10A 632/4885TNF 3532/4885CA2 569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.