Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20660358 | 0.84 | TNKS (0.59) | TNKSHPGDMMP2MMP9MMP8 | |
| SCHEMBL20320589 | 0.82 | MAPT (0.64) | TNKSHPGDMMP2MMP9MMP8 | |
| Hydrochloric Acid SCHEMBL20302609 | 0.81 | MAPT (0.62) | TNKSHPGDMMP2MMP9MMP8 | |
| SCHEMBL20660340 | 0.81 | TNKS (0.66) | TNKSHPGDMMP2MMP9MMP8 | |
| SCHEMBL20660580 | 0.80 | TNKS (0.61) | TNKSMMP2MMP9MMP8MMP13 | |
| SCHEMBL15972476 | 0.79 | MMP2 (0.71) | HPGDMMP2MMP9MMP8MMP13 | |
| SCHEMBL20660611 | 0.79 | TNKS (0.60) | TNKSHPGDMMP2MMP9MMP8 | |
| SCHEMBL20660712 | 0.79 | RAB9A (0.59) | HPGDNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14311212 | 0.79 | MMP2 (0.60) | HPGDMMP2MMP9MMP8MMP13 | |
| SCHEMBL14305019 | 0.79 | MMP2 (0.60) | HPGDMMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210115016-A1 | AMIDO COMPOUNDS AS AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2021-04-22 | — | — | US | claimed |
| WO-2019018562-A1 | AMIDO COMPOUNDS AS AhR MODULATORS | IDEAYA BIOSCIENCES, INC. (US) | 2019-01-24 | — | — | WO | claimed |
| US-11548867-B2 | Amido compounds as AhR modulators | IDEA YA BIOSCIENCES, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-20210115016-A1 | AMIDO COMPOUNDS AS AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115016-A1 | AMIDO COMPOUNDS AS AhR MODULATORS | AHR, ARNT, RXRB | TNKS 4313/4885HPGD 304/4885MMP2 4183/4885 |
| US-11548867-B2 | Amido compounds as AhR modulators | AHR, ARNT, RXRB | TNKS 4313/4885HPGD 304/4885MMP2 4183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.