Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADIPOR2 | Q86V24 | 1/20 | 0.77 |
| ▸ | ADIPOR1 | Q96A54 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17938602 | 0.87 | ADIPOR2 (1.00) | ADIPOR2ADIPOR1POLBUSP2L3MBTL1 | |
| SCHEMBL17950883 | 0.84 | ADIPOR2 (0.90) | ADIPOR2ADIPOR1POLBUSP2L3MBTL1 | |
| SCHEMBL24514564 | 0.84 | ADIPOR2 (0.82) | ADIPOR2ADIPOR1POLBUSP2L3MBTL1 | |
| SCHEMBL17946118 | 0.82 | ADIPOR2 (0.88) | ADIPOR2ADIPOR1POLBUSP2L3MBTL1 | |
| SCHEMBL17946047 | 0.81 | POLB (0.91) | ADIPOR2ADIPOR1POLBUSP2L3MBTL1 | |
| SCHEMBL24514563 | 0.81 | POLB (0.86) | ADIPOR2ADIPOR1POLBUSP2L3MBTL1 | |
| SCHEMBL20662535 | 0.80 | ADIPOR2 (0.48) | ADIPOR2ADIPOR1POLBUSP2LMNA | |
| SCHEMBL17945987 | 0.80 | POLB (0.84) | ADIPOR2ADIPOR1POLBUSP2L3MBTL1 | |
| SCHEMBL24514572 | 0.79 | ADIPOR2 (0.81) | ADIPOR2ADIPOR1POLBUSP2LMNA | |
| SCHEMBL28683173 | 0.77 | ADIPOR2 (0.73) | ADIPOR2ADIPOR1POLBUSP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3431468-A1 | USE OF ADIPONECTIN RECEPTOR AGONISTS IN TREATING DEPRESSION, ANXIETY AND NEUROINFLAMMATION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-01-23 | — | — | EP | disclosed |