Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADIPOR2 | Q86V24 | 1/20 | 0.48 |
| ▸ | ADIPOR1 | Q96A54 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | ATF4 | P18848 | 3/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20662532 | 0.80 | ADIPOR2 (0.77) | ADIPOR2ADIPOR1USP2POLBLMNA | |
| SCHEMBL22808923 | 0.70 | ADIPOR2 (0.67) | ADIPOR2ADIPOR1USP2POLBMAPK1 | |
| SCHEMBL21336045 | 0.67 | GAA (0.55) | LMNAALDH1A1MAPK1 | |
| SCHEMBL20662541 | 0.66 | SIGMAR1 (0.45) | POLBSMN1; SMN2DRD4MCHR1 | |
| SCHEMBL22517207 | 0.66 | SIGMAR1 (0.46) | ADIPOR2ADIPOR1MEN1KMT2AMAPK1 | |
| SCHEMBL17938602 | 0.66 | ADIPOR2 (1.00) | ADIPOR2ADIPOR1USP2POLBLMNA | |
| SCHEMBL24049468 | 0.65 | ADIPOR2 (0.45) | ADIPOR2ADIPOR1USP2POLBSMN1; SMN2 | |
| SCHEMBL17506035 | 0.64 | ACHE (0.36) | POLBMEN1KMT2AHRH3 | |
| SCHEMBL13943432 | 0.64 | MAPT (0.49) | LMNAALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL12179575 | 0.64 | L3MBTL1 (0.51) | POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3431468-A1 | USE OF ADIPONECTIN RECEPTOR AGONISTS IN TREATING DEPRESSION, ANXIETY AND NEUROINFLAMMATION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-01-23 | — | — | EP | disclosed |