Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 12/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6372307 | 0.74 | OAT (0.60) | ALDH1A1MAPK1NPC1KMT2AGAA | |
| SCHEMBL1783260 | 0.74 | OAT (0.41) | — | |
| SCHEMBL11883411 | 0.72 | OAT (0.52) | L3MBTL1MAPK1KMT2A | |
| SCHEMBL21650204 | 0.68 | HPGD (0.58) | HPGDALDH1A1MAPK1NPC1GLA | |
| SCHEMBL11121857 | 0.66 | CHRM3 (0.33) | HPGDALDH1A1MAPK1HTTMEN1 | |
| SCHEMBL16566608 | 0.63 | MAPT (0.32) | HPGDALDH1A1MAPK1NPC1HTT | |
| SCHEMBL13149373 | 0.63 | ALDH1A1 (0.41) | HPGDALDH1A1L3MBTL1MAPK1HTT | |
| SCHEMBL13149257 | 0.63 | ALDH1A1 (0.41) | HPGDALDH1A1L3MBTL1MAPK1HTT | |
| SCHEMBL7549050 | 0.63 | HPGD (0.47) | HPGDALDH1A1NPC1GLAMEN1 | |
| SCHEMBL1783216 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791137-B1 | PYRAZOLOPYRIDINE DERIVATIVES, PREPARATION PROCESS THEREFOR AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2019-01-23 | — | — | EP | disclosed |