Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 13/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21650204 | 0.71 | HPGD (0.58) | HPGDALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL13604500 | 0.65 | VNN1 (0.63) | HPGDALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL7132525 | 0.65 | HPGD (1.00) | HPGDALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL1826062 | 0.65 | HPGD (0.54) | HPGDALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL29944134 | 0.64 | ALDH1A1 (0.67) | HPGDALDH1A1MEN1KMT2APOLB | |
| SCHEMBL1569994 | 0.64 | ALDH1A1 (0.67) | HPGDALDH1A1MEN1KMT2APOLB | |
| SCHEMBL28684147 | 0.64 | HPGD (0.52) | HPGDALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL20663286 | 0.63 | HPGD (0.43) | HPGDALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL969811 | 0.63 | HPGD (0.52) | HPGDALDH1A1TSHRNPC1GLA | |
| SCHEMBL6641990 | 0.63 | VNN1 (0.60) | HPGDALDH1A1USP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-02 | — | — | EP | claimed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | claimed |