Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | ADK | P55263 | 4/20 | 0.37 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.37 |
| ▸ | NAE1 | Q13564 | 3/20 | 0.36 |
| ▸ | UBA3 | Q8TBC4 | 2/20 | 0.36 |
| ▸ | UBA1 | P22314 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25469568 | 0.84 | CA2 (0.49) | CA2ADKPRMT5METTL3 | |
| SCHEMBL25470071 | 0.82 | CA2 (0.47) | CA2PRMT5METTL3 | |
| SCHEMBL17254858 | 0.81 | POLB (0.38) | CA2 | |
| SCHEMBL17762958 | 0.80 | CA2 (0.43) | CA2ADKDOT1LNAE1UBA3 | |
| SCHEMBL22386563 | 0.79 | CA2 (0.44) | CA2ADKDOT1LNAE1UBA3 | |
| SCHEMBL26068620 | 0.79 | CA2 (0.45) | CA2ADKDOT1LNAE1UBA3 | |
| SCHEMBL17762957 | 0.79 | CA2 (0.43) | CA2ADKDOT1LNAE1UBA3 | |
| SCHEMBL2611654 | 0.78 | CA2 (0.41) | CA2ADKDOT1LNAE1UBA3 | |
| SCHEMBL13804727 | 0.78 | CA2 (0.40) | CA2ADKDOT1LNAE1UBA3 | |
| SCHEMBL25469646 | 0.77 | CA2 (0.51) | CA2PRMT5METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3431615-A2 | DNA SEQUENCING WITH NON-FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS CLEAVABLE LABEL MODIFIED NUCLEOTIDE TERMINATORS | The Trustees of Columbia University in the City of New York (US) | 2019-01-23 | — | — | EP | disclosed |