Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | ADK | P55263 | 4/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 7/20 | 0.36 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.35 |
| ▸ | RNMT | O43148 | 1/20 | 0.35 |
| ▸ | NAE1 | Q13564 | 3/20 | 0.35 |
| ▸ | UBA3 | Q8TBC4 | 2/20 | 0.35 |
| ▸ | UBA1 | P22314 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17762957 | 0.94 | CA2 (0.43) | CA2ADKFGFR2DOT1LFGFR1 | |
| SCHEMBL19119584 | 0.93 | CA2 (0.41) | CA2ADKFGFR2DOT1LFGFR1 | |
| SCHEMBL17762956 | 0.85 | ADK (0.53) | ADKPRMT5METTL3 | |
| SCHEMBL2611654 | 0.82 | CA2 (0.41) | CA2ADKFGFR2DOT1LFGFR1 | |
| SCHEMBL19120083 | 0.82 | CA2 (0.40) | CA2ADKFGFR2DOT1LPRMT5 | |
| SCHEMBL13804727 | 0.80 | CA2 (0.40) | CA2ADKFGFR2DOT1LFGFR1 | |
| SCHEMBL22386563 | 0.80 | CA2 (0.44) | CA2ADKFGFR2DOT1LFGFR1 | |
| SCHEMBL20664050 | 0.80 | CA2 (0.44) | CA2ADKFGFR2DOT1LNAE1 | |
| SCHEMBL17762952 | 0.77 | DNMT1 (0.34) | — | |
| SCHEMBL21266956 | 0.77 | RNASE1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160139133-A1 | DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS | QUANTUMDX GROUP LIMITED (GB) | 2016-05-19 | — | — | US | disclosed |