SCHEMBL25469646

SCHEMBL25469646

CCC(=O)NCC#Cc1cn([C@H]2CC(O)[C@@H](COC(C)(C)C)O2)c2ncnc(N)c12

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 3/20 0.51
▸ PRMT5 O14744 4/20 0.43
▸ METTL3 Q86U44 4/20 0.43
▸ ATG7 O95352 8/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25470071 0.94 CA2 (0.47) CA2PRMT5METTL3ATG7
SCHEMBL25469568 0.85 CA2 (0.49) CA2PRMT5METTL3ATG7
SCHEMBL25469641 0.84 DNMT1 (0.39) —
SCHEMBL12531458 0.80 CA2 (0.47) CA2PRMT5METTL3
SCHEMBL14104921 0.80 CA2 (0.47) CA2PRMT5METTL3ATG7
SCHEMBL21912256 0.79 CA2 (0.49) CA2PRMT5METTL3ATG7
SCHEMBL22327353 0.79 CA2 (0.49) CA2PRMT5METTL3ATG7
SCHEMBL21585106 0.79 CA2 (0.49) CA2PRMT5METTL3ATG7
SCHEMBL12047324 0.79 CA2 (0.49) CA2PRMT5METTL3ATG7
SCHEMBL20643708 0.79 CA2 (0.52) CA2PRMT5METTL3ATG7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11655502-B2 Short pendant arm linkers for nucleotides in sequencing applications ILLUMINA CAMBRIDGE LIMITED (GB) 2023-05-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11655502-B2 Short pendant arm linkers for nucleotides in sequencing applications POLRMT, POLM, POLN CA2 4818/4885PRMT5 4181/4885METTL3 697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback